Research & Clinical Trials

Explore current research projects in the Division of Pulmonary and Critical Care Medicine or search our open clinical trials and medical research studies.

Research Labs

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  • Andrew Tager, MD

    The Tager Laboratory at Massachusetts General Hospital investigates (1) pulmonary and dermal fibrosis, focusing on the roles lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), and (2) HIV immunopathogenesis, using a novel mouse model of HIV infection.

  • ARDS Network Clinical Coordinating Center

    David Schoenfeld, PhD

    The Acute Respiratory Distress Syndrome (ARDS) Network Clinical Coordinating Center coordinates randomized controlled trials for patients with ARDS.

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  • Benjamin Medoff, MD

    The Medoff Laboratory at Massachusetts General Hospital studies the pathogenesis of pulmonary inflammation, specifically the role of T cells in mediating inflammatory lung diseases.

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  • Charles Hales, MD

    Charles Hales, MD

    Major interest in pulmonary hypertension and its treatment with heparin derivatives we have produced which are weakly anticoagulant but strongly antiproliferative for smooth muscle cells, pulmonary emboli detection and smoke inhaltion from fires.

  • Critical Care Translational Medicine Group

    Critical Care Translational Medicine Group

    The Critical Care Translational Medicine Group designs, oversees and coordinates international trials in acute respiratory distress syndrome (ARDS) and sepsis.

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  • David Christiani, MD, MPH

    David Christiani, MD, MPH

    Molecular Epidemiology of ARDS: Under the direction of David Christiani, MD, MPH, our laboratory examines genetic and environmental factors that may impact the development and progression of acute respiratory distress syndrome (ARDS).

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  • James Moon, PhD

    The Moon Laboratory at Massachusetts General Hospital investigates basic issues of CD4+ T cell tolerance by directly tracking endogenous antigen-specific populations in mice and humans.

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  • Rajagopal Lab

    Our laboratory focuses on organ regeneration and the application of developmental biology to human disease. We focus on the lung as a model system, in part due to the abundance of respiratory diseases of unknown causes and without cures. Visit our lab website at

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  • Scott Harris, MD

    Scott Harris, MD

    The Harris Lab is a multi-disciplinary, inter-departmental group of investigators aiming to advance the understanding of whole-organ physiology and pathophysiology of the human lung through the development and implementation of advanced imaging techniques, sophisticated mathematical and computer modeling and bioengineering. In our studies, we apply rigorous quantitative tools to investigate the complex structure-function relationships of healthy and diseased lungs.

  • Suter Pulmonary Optical Imaging Laboratory

    Suter Pulmonary Optical Imaging Laboratory

    The focus of the Pulmonary Optical Imaging Laboratory is the development and subsequent translation of novel optical diagnostic tools for evaluating the pulmonary airways and lung.

Clinical Trials

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