Physician Photo

Thomas Francis DeLaney, MD

Medical Director, Francis H. Burr Proton Therapy Center

Co-Director, Center for Sarcoma and Connective Tissue Oncology

  • Phone: 617-726-6876
Department of Radiation Oncology


  • Cancer Center
  • Radiation Oncology
  • Sarcoma and Connective Tissue Oncology
  • Chordoma
  • Osteosarcoma (Bone Cancer)
Clinical Interests
Proton Radiation Therapy
Ewing's sarcoma
Brachytherapy (radioactive seeds)
IORT (Intraoperative Radiation Therapy)
Boston: Massachusetts General Hospital
Medical Education
MD, Harvard Medical School
Residency, Massachusetts General Hospital
Fellowship, Massachusetts General Hospital
Board Certifications
Therapeutic Radiology, American Board of Radiology
Patient Gateway
Yes, learn more
Foreign Languages
Patient Age Group
Adult and pediatric
Accepting New Patients
Accepting New Patients


Thomas F. DeLaney, M.D. is a graduate of Harvard College and Harvard Medical School. He trained in Radiation Oncology at the Massachusetts General Hospital (MGH) and spent 6 years as Senior Investigator at the National Cancer Institute. Since 1992, he has been on staff at MGH where he is the Medical Director of the Francis H. Burr Proton Therapy Center and Co-Director of the Center for Sarcoma and Connective Tissue Oncology. He is Professor of Radiation Oncology at Harvard Medical School.

Dr. DeLaney has made important contributions to the treatment of soft tissue sarcomas, bone sarcomas and chordomas, as well as the use of charged particle (proton) radiation therapy. His bibliography lists him as lead author or co-author of 92 original articles in peer-reviewed research publications, as well as 77 reviews, chapters and editorials. He is on the editorial boards of Journal of Surgical Oncology, Journal of Clinical Oncology and UpToDate in Oncology.


My major research efforts have been in the development and testing of innovative cancer treatment approaches in clinical trials. Primary areas of interest have been soft tissue and bone sarcomas in adults and adolescents, as well as the application of advanced radiation oncology technologies including charged particle radiation with protons and brachytherapy (i.e. placement of radiation sources in close proximity to the tumor to deliver high doses of radiation to the tumor while sparing nearby normal tissue).


View my most recent publications at PubMed

  1. DeLaney TF et al. Neoadjuvant chemotherapy and radiotherapy for large extremity soft-tissue sarcomas. Int J Rad Oncol Biol Phys. 2003;56:1117-27.
  2. DeLaney TF et al. Phase II study of high dose photon/proton radiotherapy in the management of spine sarcomas. Int J Rad Oncol Biol Phys 2009; 74: 732-9.
  3. Kepka L, DeLaney TF, et al. Results of radiation therapy for unresected soft-tissue sarcomas. Int J Rad Oncol Biol Phys 2005; 63:852-9.

MGH Cancer Center now offers pencil-beam proton therapy treatment

The MGH Cancer Center has added pencil-beam scanning to the radiation therapy modalities offered at the hospital’s Burr Proton Therapy Center.

Francis H. Burr Proton Therapy Center
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-726-6876
Fax: 617-724-9532