Physician Photo

Annie Waifong Chan, MD

Director, Proton Fellowship Program

Director, Head and Neck Radiation Oncology Research Program

  • Phone: 617-724-1159
Department of Radiation Oncology


  • Cancer Center
  • Radiation Oncology
  • Thyroid Tumors
  • Neuro-Oncology (Brain)
  • Endocrine Tumors
  • Head & Neck Cancers
Clinical Interests
Head and neck cancer
Sinonasal Tumors
Proton Radiation Therapy
Adult skull base tumors
Stereotactic Radiosurgery
Intensity modulated radiation therapy (IMRT)
Boston: Massachusetts General Hospital
Medical Education
MD, University of Chicago Pritzker School of Medicine
Residency, Massachusetts General Hospital
Board Certifications
Radiation Oncology, American Board of Radiology
Patient Age Group
Accepting New Patients
Accepting New Patients


Clinical and translational research in head and neck and skull base cancers.

Partial list of recent publications:
1. Chan AW/Loeffler JS. Conventionally Fractionated Stereotactic Radiotherapy for Vestibular Schwannomas: Favorable Outcome with Minimal Toxicity. Neurosurgery. 2005 Jul;57(1):60-69.
2. Pommier P/Chan AW. Proton Beam Radiation Therapy for Skull Base Adenoid Cystic Carcinoma. Archives of Otolaryngology - Head & Neck Surgery. 2006;132:1242-1249.
3. Patel S/Chan AW. Proton Beam Radiation Therapy for Nasopharyngeal Carcinoma. In: Proton and Heavier Charged Particle Radiotherapy. Delaney T and Kooy H, editors. Lippincott Willimas and Wilkins, 2007.
4. Chan AW and Liebsch NJ. Proton Beam Therapy for Head and Neck Cancer. J Surg Oncol. 97(8):697-700, 2008.
5. Truong MT/Chan AW. Proton Beam Radiation Therapy for Sphenoid Sinus Malignancies: Treatment Outcome and Prognostic Factors. Head and Neck 31(10):1297-1308, 2009.
6. Chan AW. Advantages of Proton Beam Therapy. In: Functional Preservation and Quality of Life in Head and Neck Radiotherapy Harari PM, editor. Springer, 2009.
7. Moore MG/Chan AW. Risk of Incisional Recurrence after Midface and Anterior Skull Base Surgery in Sinonasal Malignancies. Skull Base, 2011 (In press).
8. Margalit DN, Chan AW. Proton Therapy for Head and Neck Cancers. In: Head and Neck Cancer: Multimodality Management. Bernier J, editor. Springer, 2011 (In Press).
9. Margalit DN, Chan AW. Particle Therapy for Head and Neck Cancers. Radiation Medical Rounds, 2011 (In Press).
10. Wang JJ/Chan AW. Risk of Pharyngoesophageal Stricture after Radiation Therapy for Head and Neck Cancer. Head and Neck, 2011 (In Press).

Proton beam therapy shows encouraging long-term outcome for patients with locally advanced sinonasal cancers

Proton beam radiation therapy shows encouraging results for patients with locally advanced sinonasal malignancies, according to a study led by Annie Chan, MD, a radiation oncologist at Massachusetts General Hospital.

Clark Center for Radiation Oncology
100 Blossom Street
Boston, MA 02114-2606

Phone: 617-724-1159
Fax: 617-726-3603