Genitourinary Program

Specialists in the Genitourinary Program in the Department of Radiation Oncology are renowned for their expertise in using advanced radiation therapies to treat cancers of the urinary tract (men and women) and the reproductive tract (men).


The Genitourinary Program uses ing the latest state-of-the-art and innovative technologies including:

  • Proton beam therapy
  • Intensity-modulated radiation therapy (IMRT)
  • Image-guided radiation therapy (IGRT)
  • Stereotactic body radiation therapy (SBRT)
  • Prostate brachytherapy
  • Intraoperative radiation therapy (IORT)

Our team includes some of the most experienced radiation oncologists treating genitourinary GU cancers in the United States. Every year, we manage radiation therapy for thousands of patients with cancers and tumors of the:

  • Prostate
  • Bladder
  • Kidneys
  • Testes
  • Penis
  • Ureters
  • Urethra

Personalized, Targeted Therapies

Our radiation oncologists treat patients with sophisticated, state-of-the-art technologies. What distinguishes our program, however, is our oncologists' expertise in targeting and customizing the right therapy or combination of therapies for each patient. Our specialists are involved in all aspects of GU cancer care including new targeted biologic therapies combined with radiation as well as quality of life research.

Treatment decisions are based on the patient's type of cancer, overall picture of health and other factors unique to the individual. Although we offer the full range of radiation therapies, including techniques available at few other hospitals, we recommend and administer only those methods that meet each patient's particular needs.

Leaders in Treating Genitourinary Cancers & Tumors

In the 1980s, William Shipley, MD, a pioneer in the field of GU radiation oncology, developed an innovative organ-sparing protocol that helps more patients with bladder cancer retain their naturally functioning bladders. Dr. Shipley studied and advanced this therapy with his colleagues at the Mass General Cancer Center.

At the highly specialized Claire and John Bertucci Center for Genitourinary Cancers, part of the Cancer Center, our radiation oncologists work closely with your treatment team, which may include:

  • Medical oncologists
  • Urologists/ Surgeons
  • Radiologists
  • Pathologists

Our practitioners determine the best way to integrate radiation therapy into your treatment plan, especially when additional treatment methods are prescribed, such as surgery and/or chemotherapy.

Meet the Team

Every step of your radiation therapy is managed by an experienced radiation oncologist who has devoted his or her clinical practice, research and postdoctoral training to treating patients with GU cancers.

Our physician staff includes:

  • Anthony Zietman, MD, program chief. His undergraduate training was completed at Oxford University in the UK and he then went to medical school at the Middlesex Hospital, London University graduating in 1983. After residencies in internal medicine and clinical oncology, he moved to the Massachusetts General Hospital in Boston, USA for a fellowship in radiation biology. Since joining the staff he has authored over 200 original articles and reviews on many aspects of GU cancer. His particular research interests are in the specific roles of active surveillance, brachytherapy, hormone therapy, and proton beam therapy in the management of prostate cancer. He also has a long-standing interest in the organ-sparing treatment of bladder cancer. He is currently Shipley Professor of Radiation Oncology at Harvard Medical School and has recently finished his term as President and Chair of the American Society for Radiation Oncology (ASTRO). He is a Trustee of the American Board of Radiology and, since 2011, been editor of the International Journal of Radiation Oncology Biology Physics.
  • Jason Efstathiou, MD, PhD, holds a BS degree from Yale University, MD from Harvard Medical School (HMS), doctoral degree from the University of Oxford (UK), and completed his residency training in the Harvard Radiation Oncology Program. He serves as Assistant Professor of Radiation Oncology at HMS and MGH. His commitment to service/patient care has been recognized as honoree for the 2012 MGH Cancer Center’s “The One Hundred”, and as nominee for the 2013 Brian A. McGovern Award for Clinical Excellence. His research has informed clinical practice guidelines and focuses on technology assessment and comparative effectiveness of advanced/emerging therapies for prostate cancer including proton beam, as well as hormonal therapy and bladder-sparing chemoradiation. He holds national leadership positions in radiation oncology including within the cooperative groups, professional societies and National Cancer Institute. Other projects of his include the development of web-based patient decision aids/support tools, evaluating the multidisciplinary approach to cancer care, and global oncology outreach efforts.
  • Phillip Gray, MD, holds a BS degree from the University of Arizona and an MD degree from Johns Hopkins University School of Medicine. He completed his residency training in the Harvard Radiation Oncology Program. He currently serves as Instructor of Radiation Oncology at Harvard Medical School and the Massachusetts General Hospital. His research focuses on finding ways to improve national care delivery for patients with genitourinary cancers, investigations into patient quality of life during and after treatment and developing novel therapies for cancers of the prostate, bladder, testis and kidney. He speaks fluent Mandarin Chinese and is also involved in global outreach efforts with care providers in China and other countries.

Patient Education

We encourage you to ask us about any step in the treatment process, from understanding the safety of your therapy to managing side effects. The answers to many frequently asked questions also appear in Your Guide to Radiation Therapy (PDF).

Clinical Trials

Massachusetts General Hospital invites patients and the community to participate in innovative clinical trials and research studies.

Search open clinical trials.


Contact Us

Clark Center for Radiation Oncology

Vida E & Arthur L. Goldstein Lunder Building

55 Fruit StreetLunder Building LL3 Boston, MA 02114
  • Near Public Transit
  • Handicapped Accessible
  • Phone: 617-726- 8651
  • Fax: 857-238-6377
  • Email Us

Francis H. Burr Proton Therapy Center
30 Fruit Street
Boston, MA 02114
Phone: 617-726-0923 (Proton Inquiry Line: 617-724-1680)
Fax: 617-726-6498

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