The aged niche disrupts muscle cell quiescence
Chakkalakal J, Jones K, Basson MA, Brack AS.


Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs
Mou H, Zhao R, Sherwood R, Ahfeldt T, Lapey A, Wain J, Sicilian L, Izvolsky K, Musunuru K, Cowan C, Rajagopal J. Cell Stem Cell. 2012 Apr 6;10(4):385-97. Erratum in: Cell Stem Cell. 2012 May 4;10(5):635.


Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT. Cell Stem Cell. 2012 Mar 2;10(3):259-72.


Programming human pluripotent stem cells into white and brown adipocytes
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA. Nat Cell Biol. 2012 Jan 15;14(2):209-19. doi: 10.1038/ncb2411.


Cbx proteins help ESCs walk the line between self-renewal and differentiation
Camahort R, Cowan CA. Cell Stem Cell. 2012 Jan 6;10(1):4-6.


Wt1a, Foxc1a and the Notch mediator Rbpj physically interact and regulate the formation of podocytes in zebrafish
O'Brien LL, Grimaldi M, Kostun Z, Wingert RA, Selleck R, Davidson AJ. Dev Biol. 2011 Oct 15;358(2):318-30. Epub 2011 Aug 16.


Asymmetric cancer cell division regulated by AKT
Dey-Guha I, Wolfer A, Yeh AC, G Albeck J, Darp R, Leon E, Wulfkuhle J, Petricoin EF 3rd, Wittner BS, Ramaswamy S. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12845-50. Epub 2011 Jul 14.


Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b
Wingert RA, Davidson AJ. Dev Dyn. 2011 Aug;240(8):2011-27. doi: 10.1002/dvdy.22691.


In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Celso CL, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP. Nature. 2011 Jun 8;474(7350):216-9. doi: 10.1038/nature10160.


Chromatin connections to pluripotenency and cellular reprogramming
Orkin S. and Hochedlinger K. Cell. 2011 June 10;


IPS cells under attack
Apostolou E, Hochedlinger K. Nature. 2011 Jun 8;474(7350):165-6. doi: 10.1038/474165a.


Guanine nucleotide exchange factor Vav1 regulates preivascular homing and bone marrow retention of hematopoietic stem and progenitor cells
Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA. Proc Natl Acad Sci U S A. 2011 May 23. [Epub ahead of print]


Posttranscriptional activation of gene expression in Xenopus laevis oocytes by microRNA-protein complexes (microRNPs)
Mortensen RD, Serra M, Steitz JA, Vasudevan S. Proc Natl Acad Sci U S A. 2011 May 2. [Epub ahead of print]


Loss of COUP-TFI alters the balance between caudal ganglionic eminence and medial ganglionic eminence 
Lodato S, Tomassy GS, De Leonibus E, Uzcategui YG, Andolfi G, Armentano M, Touzot A, Gaztelu JM, Arlotta P, de la Prida LM, Studer M
Journal of Neuroscience 23 March 2011


Harnessing the potential of induced pluripotent stem cells for regenerative medicine
Wu SM, Hochedlinger K. Nat Cell Biol. 2011 May;13(5):497-505.


Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex
Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P. Neuron. 2011 Feb 24;69(4):763-79.


Identification of adult nephron progenitors capable of kidney regeneration in zebrafish
Diep CQ, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bolliq F, Djordjevic G, Lichman B, Zhu H, Ikenaga T, Ono F, Englert C, Cowan CA, Hukriede NA, Handin RI, Davidson AJ
Nature 470, 95-100 (03 Feburary 2011)


Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Nat Biotechnol. 2011 Feb;29(2):149-53. Epub 2011 Jan 19.


The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
Gurumurthy S, Xie SZ, Alagesan B, Kim J, Yusuf RZ, Saez B, Tzatsos A, Ozsolak F, Milos P, Ferrari F, Park PJ, Shirihai OS, Scadden DT, Bardeesy N. Nature. 2010 Dec 2;468(7324):659-63.


Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo
Rouaux C, Arlotta P. Nat Neurosci. 2010 Nov;13(11):1345-7. Epub 2010 Oct 17.


Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ. Cell Stem Cell. 2010 Nov 5;7(5):618-30. Epub 2010 Sep 30.


Epigenetic reprogramming and induced pluripotency
Hochedlinger K, Plath K. Development. 2009 Feb;136(4):509-23.


Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Celso CL, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT. Nature, 2009 Mar 25. [Epub ahead of print]


The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells. Chou YF, Chen HH, Eijpe M, Yabuuchi A, Chenoweth JG, Tesar P, Lu J, McKay RD, Geijsen N. Cell. 2008 Oct 31;135(3):449-61.


Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Foudi A, Hochedlinger K, Van Buren D, Schindler JW, Jaenisch R, Carey V, Hock H. Nat Biotechnol. 2009 Jan;27(1):84-90. Epub 2008 Dec 5.


Induced pluripotent stem cells generated without viral integration. Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K. Science. 2008 Nov 7;322(5903):945-9. Epub 2008 Sep 25.


A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA. Cell Stem Cell. 2008 Jan 10;2(1):50-9.


Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort. Wittner B, Sgroi DC, Ryan PD, Bruinsma T, Glas A, Male A, Dahiya S, Habin K, Bernards R, Haber DA, van’t Veer L, Ramaswamy S. Clin Cancer Res 2008; 14:2988-2993.


CTIP2 Controls the Differentiation of Medium Spiny Neurons and the Establishment of the Cellular Architecture of the Striatum Arlotta. P.*, Molyneaux, B.J.*, Jabaudon, D., Yoshida, Y. and Macklis J.D. The Journal of Neuroscience. 2008; 16; 28 (3):622-32. (*equal contribution)

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