APRIL 2017

Effects of alcoholism on the brain's reward system appear to be different in women than in men

A collaborative study between researchers at Massachusetts General Hospital and Boston University School of Medicine has found evidence implying that alcoholism may have different effects on the reward system in the brains of women than it does in men.

Pretreatment HIV, immune activation levels determine their persistence during treatment

A study led by a Massachusetts General Hospital investigator finds that pretreatment viral levels and immune activation appear to determine the extent of HIV persistence and inflammation during antiretroviral treatment.

Macrophages shown to be essential to a healthy heart rhythm

A Massachusetts General Hospital-led research team has discovered that the immune cells called macrophages are also essential to the healthy functioning of the heart, helping conduct the electric signals that coordinate the heartbeat.

Mass General researchers provide evidence linking "leaky gut" to chronic inflammation

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays in chronic inflammatory conditions.

RNA sequencing applied as a tool to solve patients' diagnostic mysteries

In a new study, a team led by researchers from the Broad Institute of MIT and Harvard, Massachusetts General Hospital and the National Institute of Neurological Disorders and Stroke adds RNA sequencing to the diagnostic toolkit to identify disease-causing mutations buried inside the genome.

Marathon risk for non-runners

People who suffer heart attacks or cardiac arrests in the vicinity of an ongoing major marathon are more likely to die within a month due to delays in transportation to nearby hospitals, according to newly published research from Harvard Medical School.

Urine test may be able to diagnose obstructive sleep apnea in children with Down Syndrome

A study from Massachusetts General Hospital investigators raises the possibility of identifying children with Down syndrome who may also have obstructive sleep apnea without the need for expensive and inconvenient sleep studies.

Collagen-targeting PET probe may improve diagnosis and treatment of pulmonary fibrosis

A PET imaging probe developed by Massachusetts General Hospital investigators appears able to diagnose and stage pulmonary fibrosis – an often life-shortening lung disease – as well as monitor the response to treatment.

Regular aspirin use is associated with lower cancer mortality

Long-term, regular aspirin use was associated with reduced risk of death from several different kinds of cancers, according to data presented at the AACR Annual Meeting 2017.


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