Research in-depth
Research in-depth

Boosting the voice of the patient in the medical decision making process

Researchers at the Health Decision Sciences Center at Massachusetts General Hospital are working on ways to better involve patients in decisions about their medical care.


To Mars and beyond: Exploring innovative solutions to the challenges of space travel

One Massachusetts General Hospital researcher is looking for innovative approaches to address the many challenges of long distance space travel.


A trailblazing engineer continues her advocacy for gender equality in the sciences

Motivated by the challenges she faced in establishing her career as a female mechanical engineer in the 1950s and 1960s, philanthropist Brit d'Arbeloff continues to be a positive force for gender equality in the sciences.


Proposed NIH budget cuts would greatly impact the research landscape

President Donald Trump's proposed budget for Fiscal 2018, which calls for a 20% reduction in funding for the National Institutes of Health, would have a devastating effect on research at Massachusetts General Hospital and across the country, says Harry W. Orf, PhD, senior vice president for research.


Team effort leads to new insights into acute myeloid leukemia

How do you stop a deadly case of arrested development? That’s the question that prompted a six-year pursuit into the mechanisms underlying acute myeloid leukemia (AML) for David Sykes, MD, PhD, David Scadden, MD, and a team of collaborators from Massachusetts General Hospital, the Broad Institute, Bayer Pharma and the University of New Mexico.


Ice Bucket Challenge funds will help to expand information-sharing network for ALS research

Recently, $3.6 million of the funds raised by The ALS Association through the Ice Bucket Challenge and the ALS Finding a Cure foundation came to Mass General in a grant to support NeuroBANK, an online platform that was created to address the challenges of compiling patient data for ALS research.


Zebrafish behavior screening could streamline new treatments for mental health

A team of researchers at Massachusetts General Hospital including Andrew Rennekamp, PhD, is using behavior changes in zebrafish larvae to learn more about the brain mechanisms behind psychosis and threat response.


Mass General to play key role in National Precision Medicine Initiative

The All of Us Research Program is a national initiative with a goal of building a cohort of one million or more volunteer participants who reflect the diversity of America.


Hackathon generates new plan to reduce deadly opiate overdoses

The three-day event provided an opportunity for three Mass General specialists to collaborate an innovative plan for reversing overdoses before they cause lasting damage.


Seal study could provide insights into blood flow disorders

A research team from Massachusetts General Hospital has returned to Antarctica to continue their study of Weddell Seals, world-champion diving mammals with unique adaptations that allow them to spend more than an hour underwater without surfacing for air.


Reducing epilepsy stigma with a multilingual coloring book

The Global Neurology Research Group has created a multilingual coloring book to explain epilepsy to children around the world and reduce myths and stigma surrounding seizures. My Thinking Cap, A Coloring Book About Epilepsy introduces us to Ella, Dot, and Jon-Jon, a young boy with epilepsy.


Mateen seeks creative solutions for global neurology challenges

Farrah Mateen, MD, PhD, divides her time between seeing patients at Massachusetts General Hospital and traveling across the globe researching innovative solutions for global neurological care.


Cell race organizers working to accelerate the pace of sepsis research

Researchers will convene at Massachusetts General Hospital this fall to race strains of cells against each other in an effort to learn more about the mechanisms of sepsis—a devastating, costly and often fatal condition.


Brown hopes to change the way we think about anesthesia

Emery Brown, MD, PhD, and a team of collaborating investigators from Massachusetts General Hospital are hoping to make a fundamental change in the way anesthesiologists think about the process of sedation—one that changes the focus from the body to the brain.


Grogg uses math to improve proton beam therapy treatments for cancer patients

Kira Grogg, PhD, a researcher at the Gordon Center for Medical Imaging at Massachusetts General Hospital, is working to develop a methodology that will allow for better tracking and more precise delivery of proton beam therapy treatments for cancer patients.


Germine maps the mind with the help of online tests

A team of investigators led by Laura Germine, PhD, is using web-based tests to gain valuable insights into the way we think and process information.


Biobank samples help to locate patients with a gene variant that naturally lowers triglycerides

Sekar Kathiresan, MD, medical director for the Cardiology Division, and his team of investigators – led by cardiologist Pradeep Natarajan, MD, and research coordinator Erina Kii in the Center for Human Genetic Research – are looking for a needle in a haystack.


Biobank assists in quest to better understand calcifylaxis

Sagar Nigwekar, MD, MMSc, is using patient samples from the Partners Biobank to gain a better understanding of a rare but painful and debilitating condition called calciphylaxis.

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