Snapshot of Science

Here's a quick look at some of the recent publications, press releases and stories about the Mass General research community.

In this issue we highlight:

  • 14 new studies in high impact journals
  • 11 new research-related press releases from the Mass General Public Affairs office
  • 12 posts about our researchers from the Mass General Research Institute blog

This is just a small snapshot of the incredible research that takes place at Mass General each day—there's lots more to find at massgeneral.org/research/news.


PUBLICATIONS WITH SUMMARIES

(Click on titles to see author-submitted summaries)

  • ALLERGENS AND THE NERVOUS SYSTEM RESPONSE
    Activation of Mas-Related G-Protein Coupled Receptors By the House Dust Mite Cysteine Protease Der p1 Provides a New Mechanism Linking Allergy and Inflammation.
    Published in Journal of Biological Chemistry on August 2, 2017
  • INFLAMMATORY RESPONSE TO TOXINS
    Pseudomonas Aeruginosa ExoU Augments Neutrophil Transepithelial Migration.
    Published in PLOS on August 3, 2017
  • USING OPTICAL SENSORS FOR ANTICOAGULANT DOSING
    Optical Sensing of Anticoagulation Status: Towards Point-of-Care Coagulation Testing.
    Published in PLOS on August 3, 2017
  • METABOLISM AND GENETICS
    Development A Genetically Encoded Tool for Manipulation of NADP+/NADPH in Living Cells.
    Published in Nature Chemical Biology on August 7, 2017
  • IDENTIFYING GENETIC IMBALANCES
    Genome-Wide Identification of Autosomal Genes with Allelic Imbalance of Chromatin State.
    Published in PLOS on August 10, 2017
  • DETECTING STIFF TUMORS
    Molecular MR Imaging of Fibrosis in a Mouse Model of Pancreatic Cancer.
    Published in Scientific Reports on August 14, 2017
  • IMMUNOTHERAPY TREATMENT FOR GLIOBLASTOMA
    Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade.
    Published in Cancer Cell on August 14, 2017
  • LUNG INFLAMMATION AND AIRWAYS
    Development of a Primary Human Co-Culture Model of Inflamed Airway Mucosa.
    Published in Scientific Reports on August 15, 2017
  • METHOD TO REDUCE COST FOR PET IMAGING
    Synthesis-Free PET Imaging of Brown Adipose Tissue and TSPO via Combination of Disulfiram and 64CuCl2.
    Published in Scientific Reports on August 15, 2017
  • NEW METHOD FOR PET IMAGING
    Pseudo-Reference Regions for Glial Imaging with 11C-PBR28: Investigation in Two Clinical Cohorts.
    Published in the Journal of Nuclear Medicine on August 17, 2017
  • BRAIN ACTIVITY AND CONNECTIVITY BETWEEN REGIONS
    Dynamic Connectivity Modulates Local Activity in the Core Regions of the Default-Mode Network.
    Published in PNAS on August 21, 2017
  • TREATING LYMPHOMA WITH TUMOR-TARGETING IMMUNE CELLS
    Anti-CD19 CAR T Cells in CNS Diffuse Large-B-Cell Lymphoma.
    Published in the New England Journal of Medicine on August 24, 2017
  • OBSERVING THE DEVELOPMENT OF TYPE 1 DIABETES
    Imaging the Emergence and Natural Progression of Spontaneous Autoimmune Diabetes.
    Published in PNAS on August 24, 2017
  • NON-INVASIVE MEASUREMENT OF BRAIN ACTIVITY AND MEMORY ENCODING
    fNIRS Can Robustly Measure Brain Activity During Memory Encoding and Retrieval in Healthy Subjects.
    Published in Scientific Reports on August 25, 2017

Additional Publications


Press Releases

  • Predicting TB's Behavior- featuring Maha Farhat (August 3, 2017)
  • Sense of Smell Deficits are Common, Linked to Malnutrition in Patients with Kidney Disease- featuring Teodor Pà†unescu, PhD, and Sagar Nigwekar, MD (August 3, 2017)
  • Four Partners HealthCare Hospitals Earn High Marks from U.S. News & World Report (August 8, 2017)
  • Study Finds Patients Needed Fewer Opioid Tablets Than Prescribed After Hernia Surgery- featuring Peter Masiakos, MD (August 9, 2017)
  • Mental Health Programs in Schools -- Growing Body of Evidence Supports Effectiveness- featuring J. Michael Murphy, EdD (August 10, 2017)
  • Out-of-Pocket Health Costs Can Lead to Financial Problems for Survivors of Childhood Cancer- featuring Ryan Nipp, MD (August 22, 2017)
  • Study Estimates Number of Births, Population Prevalence of Down Syndrome in Nine States- featuring Brian Skotko, MD, MPP (August 28, 2017)
  • Mass General Team Reports First Response of Central Nervous System Tumor to CAR T-Cells- featuring Jeremy Abramson, MD (August 28, 2017)
  • Medical Treatment May Prevent, Alleviate Mitral Valve Damage After a Heart Attack- featuring Robert Levine, MD, and Jacob Dal-Bianco, MD (August 28, 2017)
  • Brain Structural Changes Linked to Physical, Mental Health in Functional Neurological Disorder (Conversion Disorder)- featuring David Perez, MD, MMSc (August 28, 2017)
  • Cutbacks in Foreign Aid for HIV Treatment Would Produce Great Harm, Generate Few Savings- featuring Rochelle Walensky, MD, MPH (August 28, 2017)

On the Research Institute Blog

  • More Than Just a Pastime: How Video Games Change Your Brain (August 2, 2017)
  • Overcoming the “Curse of Knowledge” To Effectively Communicate Your Science (August 4, 2017)
  • Faherty Hopes to Stop Shigella from Wreaking Havoc in the Digestive System- featuring Christina Faherty, PhD (August 7, 2017)
  • Mass General Earns High Marks From U.S. News & World Report (August 9, 2017)
  • A Snapshot of Science: Zebrafish, Steroid Replacements, and Much More- featuring Caroline Burns, PhD, Patrick Purdon, PhD, Rohit Sharma, PhD, and John Stone, MD, MPH (August 11, 2017)
  • New Study Shows Lymph Nodes Aren’t Always to Blame for Cancer’s Progression- featuring Rakesh K. Jain, PhD, and Kamila Naxerova, PhD (August 14, 2017)
  • Sniffing Out the Root Cause of Malnutrition in Patients with Kidney Disease- featuring Teodor Pà†unescu, PhD, and Sagar Nigwekar, MD (August 16, 2017)
  • Six Selfish Reasons to Communicate Science (August 18, 2017)
  • Shining a Light on MS-Related Fatigue- featuring Farrah J. Mateen, MD, PhD (August 21, 2017)
  • Making Migraines Less of a Headache: Researchers Find New Way to Predict Migraine Attacks- featuring Tim Houle, PhD (August 23, 2017)
  • Research Awards and Honors: August 2017- featuring Gaurdia Banister, RN, PhD, NEA-BC, FAAN, Jennifer Gatchel, MD, PhD, Aaron Hata, MD, PhD, Steven H. Liang, PhD, Mikael Pittet, PhD, and Dorothy Sippo, MD, MPH (August 25, 2017)
  • Revolutionizing Care at Mass General (August 28, 2017)

Publications from previous months:

July 2017

June 2017

May 2017

April 2017

March 2017

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