Center for Applied Clinical Investigation (CACI) Research Lab

Learn more about the Center for Applied Clinical Investigation (CACI) Research Lab and our current projects.


Dr. August with student
Dr. Meredith August, CACI Director, and HDSM student Michelle Kim presented at the 14th annual Mass General Clinical Research Day, October 6, 2016.

The Center for Applied Clinical Investigation (CACI) was established in 2000 by Dr. Thomas Dodson as both a research center and a center for training academic oral surgeons in clinical investigation. The center is dedicated to understanding the variables that contribute to manageable risks and complications and to guiding oral and maxillofacial surgeons to the best outcomes based on scientific evidence.
The Clinical Investigation Model was developed as a research program designed to provide a clinical complement to basic science research across the oral and maxillofacial surgery domain. Literature worldwide is monitored and we work to initiate and support research in emerging and under-studied disciplines. The goal is to expand the literature to promote evidence-based clinical practice and improved outcomes in oral and maxillofacial surgery. Hypothesis-driven research questions are created rigorous, sound scientific studies are designed to contribute concrete findings and outcomes that promote evidence-based clinical practice.

Research Positions

The CACI Fellowship in Clinical Investigation is an opportunity for an oral and maxillofacial surgeons to work at Mass General with CACI mentors on a course of independent clinical research in a focused area. Fellows spend two years at Mass General and their research may be integrated with a related graduate study at Harvard School of Public Health or Harvard Medical School may be combined with a master’s in Public Health. Upon completion of the CACI Fellowship in Clinical Investigation, most fellows will have achieved the academic credentials necessary for a junior faculty appointment at an accredited hospital – or university-based oral and maxillofacial surgery program. Learn more about the fellowship

Contact Us

Center for Applied Clinical Investigation (CACI)
Warren Building - Suite 1201
55 Fruit Street
Boston, MA 02114 

Phone: 617-726-8222
Fax: 617 726-2814



  • Ya-wei Chen,  2014-2016
  • Firat Selvi, 2011-2012
  • Michael Markiewicz, 2006-2007
  • Seenu Susarla, 2004-2006
  • Sung Kiang Chuang, 2002-2004
  • Leslie Halpern, 2000-2002

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