The Kobayashi laboratory uses genetically manipulated mice to study the role of regulatory systems of gene expression during cartilage and bone development. At the genetic and molecular levels, understanding how gene expression is regulated during skeletal cell differentiation is the central question. One of my current interests is to elucidate the role of the posttranscriptional gene regulatory mechanisms through the microRNA pathway in bone development.
Principal Investigator: Tatsuya Kobayashi
Role of Mir140 in bone development.
Role of let-7 miRNAs in skeletal development.
PublicationsView recent publications from the laboratory. Some full text articles may require a subscription.
Hours: 9:00 am - 4:30 pm, M-F
Public Transportation Access: yes
Disabled Access: yes
Proto magazine stakes its ground on medicine's leading edge, reporting back from the frontiers of research and practice - exploring breakthroughs, dissecting controversies and opening a forum for informed debate.
Discover the largest hospital-based research program in the U.S. and how clinicians and scientists chart new terrain in biomedical research to treat and prevent human disease and bring the latest advances to patient care
Discover what makes Massachusetts General Hospital not just one of the best places to receive patient care but also one of the best places to work.