Research Centers


Endocrine Unit: Kobayashi Laboratory

The Kobayashi Laboratory investigates the genetics of skeletal development.
  • Phone: 617-726-3966


The Kobayashi laboratory uses genetically manipulated mice to study the role of regulatory systems of gene expression during cartilage and bone development.  At the genetic and molecular levels, understanding how gene expression is regulated during skeletal cell differentiation is the central question.  One of my current interests is to elucidate the role of the posttranscriptional gene regulatory mechanisms through the microRNA pathway in bone development.

Group Members

Principal Investigator: Tatsuya Kobayashi, MD, PhD

Project Staff:

  • Fatemeh Mirzamohammadi, MD
  • Garyfallia Papaioannou, MD


Research Projects

Role of Mir140 in bone development.

Role of let-7 miRNAs in skeletal development.

PublicationsView recent publications from the laboratory. Some full text articles may require a subscription.

View all Publications in PubMed

Endocrine Unit Research Laboratories

Thier Building
50 Blossom Street
Boston, MA 02114

Phone: 617-726-3967
Fax: 617-726-7543
Hours: 9:00 am - 4:30 pm, M-F

Public Transportation Access: yes
Disabled Access: yes