Research Centers

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Pathology Research Center - Molecular Pathology Unit

Basic and translational research with an emphasis on cancer biology

The Molecular Pathology Unit, located in newly renovated facilities on the 6th and 7th floors of Building 149 in the Charlestown Navy Yard, is the largest research unit of the MGH Pathology Service. The Unit is composed of 9 independent investigators and over 60 scientists.  Research interests of the PIs range from basic science to translational with a primary emphasis on cancer biology, with most faculty being joint appointed with the MGH Cancer Center. We are growing into newly renovated space on the 7th floor of Building 149 and are actively recruiting additional faculty.

David Langenau (Director)
Martin Aryee
John Iafrate
Keith Joung 
David Louis
Miguel Rivera
Dennis Sgroi
Anat Stemmer-Rachamimov
Mario Suva

The Molecular Pathology Unit, located in newly renovated facilities on the 6th and 7th floors of Building 149 in the Charlestown Navy Yard, is the largest research unit of the MGH Pathology Service. The Unit is composed of nine independent investigators and over 60 scientists.  Research interests of the PIs range from basic science to translational research with a primary emphasis on cancer biology. Most faculty also have dual appointments with the MGH Cancer Center. We are growing into newly renovated space on the 7th floor of Building 149 and are actively recruiting additional faculty.

 

Research Labs

  • Langenau Lab
  • David Langenau, PhD, Director
  • Martin Aryee
  • John Iafrate, 
  • J. Keith Joung,  
  • David Louis, MD
  • Miguel Rivera, MD
  • Dennis Sgroi, MD
  • Anat Stemmer-Rachamimov, MD
  • Mario Suva

Molecular Pathology Laboratories & Projects

Mechanisms Driving Progression and Relapse in Pediatric Tumors

  • Mechanisms of progression and relapse in T-cell acute lymphoblastic leukemia
  • Functional consequences of tumor cell heterogeneity in embryonal rhabdomyosarcoma
  • Optimized cell transplantation using immune compromised fish

Langenau Lab

Molecular Pathology Unit

Massachusetts General Hospital
149 13th Street, 6th Floor
Charlestown, MA 02129

Phone: 617-726-5695


David M. Langenau, PhD
Director, Molecular Pathology Unit
Massachusetts General Hospital

Associate Professor of Pathology
Harvard Medical School

Email: dlangenau@mgh.harvard.edu