Guillermo J. Tearney, MD, PhD, Gary Tearney

Tearney Lab

Dr. Tearney's research is focused on developing and validating non-invasive, high-resolution optical imaging diagnostic methods, such as optical coherence tomography.


Guillermo J. Tearney, MD, PhD

Massachusetts General Hospital

Professor of Pathology
Harvard Medical School

Associate Director,
Wellman Center for Photomedicine

Biography & Research Interests

Guillermo Tearney M.D., Ph.D. is Professor of Pathology at Harvard Medical School, an Affiliated Faculty member of the Harvard-MIT Division of Health Sciences and Technology (HST), and the Associate Director of the Wellman Center for Photomedicine at the Massachusetts General Hospital.  Dr. Tearney received his MD magna cum laude from Harvard Medical School and received his PhD in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology.

Dr. Tearney’s research interests are focused on the development and clinical validation of non-invasive, high-resolution optical imaging methods for disease diagnosis. Dr. Tearney's lab was the first to perform human imaging in the coronary arteries and gastrointestinal tract in vivo with Optical Coherence Tomography (OCT), which provides cross-sectional images of tissue architectural microstructure at a resolution of 10 µm. He has also conducted many of the seminal studies validating OCT and is considered an expert on OCT image interpretation.

Recently, Dr. Tearney's lab has invented a next generation OCT technology, termed µOCT, which has a resolution of 1 µm and is capable of imaging cells and sub cellular structures in the coronary wall. Dr. Tearney has also developed several other technologies, including a confocal endomicroscope capable of imaging the entire esophagus, an ultraminiature three-dimensional endoscope, a highly efficient form of near field scanning optical microscopy (NSOM), and novel fluorescence spectroscopy and multimodality imaging techniques. He has an active program in Raman spectroscopy and has conducted the first intracoronary Raman in vivo.

Dr. Tearney is co-editor of The Handbook of Optical Coherence Tomorgraphy and has written over 170 peer-reviewed publications, including papers that have been highlighted on the covers of Science, Nature Medicine, Circulation, Gastroenterology, and Journal of American College of Cardiology.

Dr. Tearney’s work extends beyond his laboratory at Mass General, many of his technologies are being produced commercially and he has founded the International Working Group on Intravascular OCT Standardization and Validation, a group that is dedicated to establishing standards to ensure the widespread adoption of this imaging technology.


Read recent news about Dr. Tearney's research.

Updated 9/21/12

Group Members

Guillermo J. Tearney, MD, PhD



Research Positions

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