In spring 2010, the Laboratory for Musculoskeletal Research and Innovation, was established under the direction of Dr. S. Adam Hacking, Ph.D. The mandate of the lab is to address critical issues in orthopaedics and develop technology to improve patient care.
Dr. Hacking brings in vivo and in vitro expertise in bone tissue engineering, biomaterials development and analysis, fracture and graft healing and implant osseointegration. His work at the MGH is focused on novel methods to fight implant infection; methods to enhance implant fixation; the use of non-invasive techniques to assess skeletal integrity and implant fixation; methods to improve defect healing, fracture healing and allograft incorporation; and the use of micro-fabrication techniques to generate bone from its fundamental unit, the osteon.
The lab is highly motivated by collaborative projects with translational approaches and clinical relevance. Current collaborations exist with the Department of Radiology at the Brigham and Women’s Hospital, the Wyss Institute for biologically inspired engineering, the School of Engineering and Applied Science (SEAS) at Harvard University, the Department of Materials Science at McGill University, the Industrial Materials Institute (National Research Council, Canada) and the Department of Chemical and Environmental Engineering at the University of California, Riverside.
Please note: Openings at the Masters, Doctoral and Postdoctoral level are available for applicants with their own financial support (funding).
Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) are world-class biomedical research institutions dedicated to improving health worldwide. Research positions are available within the MGH Department of Orthopedics in the fields of implant infection and bone tissue engineering.
We offer excellent training in an interdisciplinary, translational, productive and world-recognized research environment. The successful candidate will be engaged in multiple collaborative projects with significant opportunities for leadership and career development.
1) Implant Infection
Areas of research interest should include molecular biology, bacterial contamination, cell biology and culture and drug release. It is preferred that the applicant have a strong background in implant infection and/or drug release and related experimental techniques.
2) Bone Tissue Engineering
Areas of research interest should include stem cell biology, cell culture, molecular biology and bone biology. It is preferred that the applicant have a strong background in bone tissue engineering, scaffold fabrication, endothelial and osteoblast cell culture and techniques. Strong candidates from other areas of tissue engineering may be considered.
Responsibilities The successful applicant will work in a multidisciplinary research environment to design and conduct experiments, perform data analyses and implement novel research methods relevant for studies of implant infection or the fabrication and application of tissue engineered bone. The applicant will play a major role in determining new research directions, writing grants, drafting manuscripts and presenting results at professional meetings.
Qualifications & Requirements