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Research at Mass General
Research from the Massachusetts General Hospital Schizophrenia Program and others has shown that, with appropriate treatment, smokers with schizophrenia can successfully quit smoking without worsening of their symptoms of schizophrenia. This work has recently been highlighted in clinical practice guidelines recommending that all people with schizophrenia spectrum disorders who smoke and want to quit be offered bupropion with or without nicotine replacement therapy along with behavioral support.
Our recent treatment study with smokers with schizophrenia or bipolar disorder here at MGH found extended duration varenicline along with behavioral support tripled cessation rates at one year for those who were able to quit for at least two weeks with varenicline and group cognitive behavioral therapy.
We offer a range of smoking cessation services, both routine and through clinical trials.
Our smoking cessation studies are not limited to patients in our psychiatric care at Massachusetts General Hospital, they are also available to the public as a health resource through our research program. Read more information about our program
Extended duration varenicline for prevention of relapse to smoking in people with schizophrenia
Contact Smoking Cessation
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