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Research at Mass General
Overview on call for clinical trials
Agenda and speakers
We aim to:
Starting a US Critical Illness and Injury Trials Group (USCIITG) will require overcoming a number of organizational and logistical hurdles, including:
To address these challenges, the organizational approach emphasizes frequent, face-to-face meetings that are aimed at generating fundable, high-impact clinical research proposals. These proposals are expected to span the patient age and time care continuums (pre-hospital to recovery). To contact us, please e-mail USCIITGroup@partners.org.
The Organizing Committee provides general oversight for the USCIIT Group serving its dual missions. This includes Steering Committee membership and strategic partnerships with other federal and private agencies.
The Steering Committee is responsible for the scientific content of the USCIITG meetings and organizing the meeting product into deliverables and timelines. It provides general oversight of the meetings, identifies specific milestones, and interacts with other networks and professional organizations. Membership rotates every three years. The 2011-2013 membership is:
One of the missions of the USCIIT Group is fostering investigator-initiated clinical trials. To this end, a mechanism was established to solicit clinical proposals with the goal of supporting a number of Clinical Projects annually (see the "Clinical Proposals" tab for additional details). The success of these efforts depends upon a cooperative model of information exchange. The approach is inclusive and aims to learn from all those who advocate for the critically ill or injured. Hypotheses will be tested by multidisciplinary “teams” that openly solicit input and encourage collaboration among investigators with similar ideas across institutions. As many of these ideas will be novel and exciting, there is an inherent risk in sharing them. Thus, the USCIIT Group Code-of-Conduct relies on an implicit pact based on an honor system, wherein attendees are expected to:
At the inaugural USCIIT Group meeting in November 2008, 18 clinical projects were presented and discussed:
2009 Clinical Proposals
2010 Clinical Proposals
2010 Clinical Proposal Updates
Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS. The United States critical illness and injury trials group: an introduction. J Trauma. 2009 Aug;67(2 Suppl):S159-60.
Cobb JP, Ognibene FP, Ingbar DH, Mann HJ, Hoyt DB, Angus DC, Thomas AV Jr, Danner RL, Suffredini AF. Forging a critical alliance: Addressing the research needs of the United States critical illness and injury community. Crit Care Med. 2009 Dec;37(12):3158-60.
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