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Research at Mass General
Instructor of Anesthesia
Our long term research interests involve the management of opioid therapy and how alterations in gene expression contribute to the chronic pain. Our current research focuses on the regulation of gene signal pathway in chronic pain and opioid tolerance using animal models. Exploring the effect of gene expression on the behavioral interaction between pain and opioid tolerance could provide important insights into the role of opioid therapy for chronic pain management and this preclinical research may lead to future clinical studies on opioid tolerance and chronic pain management, promoting new pharmacotherapies that could improve the clinical effectiveness of opioid therapy.
Anesthesia, Critical Care and Pain Medicine
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