Research Centers


Cardiovascular Biorepository (CVBio)

The Massachusetts General Hospital Cardiovascular Biorepository (CVBio) advances cardiovascular research by providing data and samples to help researchers understand how genes and other factors contribute to heart disease.

Impacting Heart Care

Doctors and scientists at Massachusetts General Hospital have long been at the forefront of advances in medical research. At the Mass General Corrigan Minehan Heart Center, we are working to advance this legacy by pioneering new models of advanced, multispecialty integrated care, expanding patient education and prioritizing new, ground-breaking research initiatives by asking our patients to participate in a new project: the Cardiovascular Biorepository (CVBio).

A biorepository is a collection of blood and other biological samples that are obtained and stored for future investigation. It serves as a resource for clinicians and scientists who conduct research to learn how genes and other factors contribute to conditions such as heart and blood vessel diseases. Patients who participate allow our researchers to use information from their blood samples and medical history as tools for medical research. By taking part in this initiative, you are contributing to research that may help in predicting, preventing and treating diseases for generations to come.

CVBio is designed to drive clinical and translational research, leading to greater integrated clinical care. At Mass General, we are leading the charge in translating discoveries in the lab to improvements in patient care, focusing not only on today's critical issues, but also by discovering the medicines of tomorrow. By supporting unparalleled cross-fertilization among various clinical areas, we are creating an environment in which information-sharing and communication among specialists lead to innovation.

Contributing to the Future of Precision Medicine

The goal of CVBio is to create a robust resource to support researchers who will contribute to the future of personalized medicine. We envision a future where doctors can treat patients with cardiovascular disease using methods that are precisely targeted to patients’ individual needs. CVBio will help achieve this goal by:

  • Incorporating innovative research into patient care  
  • Providing opportunities for participants to take part in clinical studies
  • Facilitating high-quality research in the areas of genetics and personalized medicine
  • Fostering collaboration among researchers throughout the Corrigan Minehan Heart Center
  • Encouraging scientific innovation and providing support to investigators to cultivate new ideas

Resources for Researchers

Researchers from the Corrigan Minehan Heart Center can request samples for use in their investigations. Learn more

Learn More

To learn more about the CVBio, call 617-643-1699 or email


Christopher Newton-Cheh, MD, MPH

Christopher Newton-Cheh, MD, MPH, principal investigator

Chris Newton-Cheh, MD, MPH, is a complex trait geneticist and cardiovascular epidemiologist, and holds positions as an assistant professor of medicine at Harvard Medical School and a cardiologist in the Heart Failure/Transplant Section at Massachusetts General Hospital. His laboratory investigates dilated cardiomyopathy, hypertension, sudden cardiac death and drug cardiotoxicity. Dr. Newton-Cheh and his colleagues are leveraging the rapid growth of human genetics to identify genetic variants that underlie these diseases, translate genetic discoveries into an improved understanding of human physiology through clinically-focused research, and define the role of genetics and other factors in predicting patients’ risk of disease. Dr. Newton-Cheh is on the faculty of the Center for Human Genetic Research and the Cardiovascular Research Center, both of Mass General and Harvard Medical School, and is an associate member at the Broad Institute of Harvard and MIT. He trained in internal medicine and cardiology at Mass General. He completed a postdoctoral fellowship in complex trait genetics at the Broad Institute with
Joel N. Hirschhorn, MD, PhD


Laurie Farrell BS, RN, project manager

Laurie Farrell is the clinical research project manager for CVBio at Mass General.  She is responsible for the development and implementation of the CVBio initiative across the Corrigan Minehan Heart Center, overseeing patient enrollment into the biorepository and providing managerial, logistical and administrative direction for CVBio and the study staff.


CVBio Research Study Staff

The CVBio Research Study Staff comprises a team of clinical research coordinators who assist patients in enrolling into CVBio and organizes and maintains the study databases and information. Our study staff comprises highly motivated, highly trained individuals who act as a study resource for patients, families and staff. Many members of our study staff are interested in pursuing careers in medicine, genetics or clinical research.