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Biorepository for Neurological Injury
The Massachusetts General Hospital Biorepository for Neurological Injury advances research in brain health and recovery by providing data to help researchers understand how genes and other factors contribute to risk of brain disease, recovery from brain injuries and the maintenance of a healthy brain.
Impacting Neurological Care
Doctors and scientists at Massachusetts General Hospital have long been at the forefront of advances in medical research. Within the Department of Neurology, we are working to advance this legacy by pioneering new models of advanced, integrated care, expanding patient education and prioritizing new, ground-breaking research initiatives by asking our patients to participate in the Biorepository for Neurological Injury, or the “BNI.”
A biorepository is a collection of blood and other biological samples that are obtained and stored for future investigation. It serves as a resource for clinicians and scientists who conduct research to learn how genes and other factors contribute to brain health and recovery. At Mass General, we are leading the charge in translating discoveries in the lab to improvements in patient care, focusing not only on today's critical issues, but also by discovering the medicines of tomorrow. Patients who participate allow our researchers to use information from their blood samples and medical history as tools for medical research. By taking part in this initiative, you are contributing to research that may help in predicting, preventing and treating diseases for generations to come.
Contributing to the Future of Precision Medicine
The goal of the Biorepository for Neurological Injury is to create a robust resource to support researchers who will contribute to the future of personalized medicine within the field of neurology. We envision a future where doctors can treat patients with neurological disease using methods that are precisely targeted to patients’ individual needs. The BNI will help achieve this goal by:
By joining the BNI, you will also be enrolled into the Partners HealthCare Biobank (PHB). The PHB is a large research program designed to help researchers understand how people’s health is affected by their genes, lifestyle, and environment, and any patient with a medical record number at Massachusetts General Hospital is eligible to participate.
To learn more about the Biorepository for Neurological Injury, call 617-643-3875 or email MGHStrokeResearchCen@partners.org.
Jonathan Rosand, MD, MSc, is a stroke and critical care neurologist with expertise in the genetics of complex diseases. He is a professor of neurology at Harvard Medical School, the J. Philip Kistler Neurologist at Massachusetts General Hospital and chief of the Mass General Division of Neurocritical Care and Emergency Neurology. He received his medical degree from the Columbia University College of Physicians and Surgeons and served as intern, resident, chief resident and fellow at Mass General following postdoctoral research training in genetics and clinical investigation, Professor Rosand established a successful multidisciplinary research group focused on brain disease, recovery from brain injuries and the maintenance of a healthy brain.
Zora DiPucchio is the Project Manager for the Biorepository for Neurological Injury. She is responsible for biorepository operations, overseeing patient enrollment and providing managerial, logistical and administrative direction.
Zora received a Bachelor of Science in Psychology from Northeastern University and a Master of Business Administration from Suffolk University’s Sawyer Business School. Before joining MGH in 2011, Zora worked as a Project Manager in CNS disorder treatment trials at a global biotech company in downtown Boston.
The Biorepository for Neurological Injury Study Staff is comprised of a team of clinical research assistants and coordinators who facilitate patient enrollment into the BNI, a data manager who maintains the study databases and information, and lab staff who are responsible for the analysis and management of our biospecimens. Our study staff is comprised of highly motivated and trained individuals who act as study resources for patients, families and staff. Many members of our study staff are interested in pursuing nursing or medical school, or graduate studies in a medical related field.
Supporting Innovative Research in Neurology
The Biorepository for Neurological Injury at Massachusetts General Hospital allows for large-scale, state-of-the-art genetic and translational research by providing investigators access to a rich, exquisitely characterized collection of biosamples from neurology patient cohorts. This collection of blood and tissue samples is stored at a Mass General laboratory facility, and is linked to phenotypic and clinical data stored in a database. Our goal is to facilitate collaboration and to foster longitudinal relationships among physicians, investigators and patient donors.
Information for Researchers
To learn more about the BNI, call Project Manager Zora DiPucchio at 617-726-7710 or email firstname.lastname@example.org.
Frequently Asked Questions: Taking Part in the Biorepository for Neurological Injury
The Biorepository for Neurological Injury (“BNI”) at Massachusetts General Hospital helps researchers study how genes and other factors contribute to risk of brain disease, recovery from brain injuries and the maintenance of a healthy brain.
Patients seen in any unit or clinic within the Neurology Department at Massachusetts General Hospital can join the Biorepository for Neurological Injury. If you join the BNI, our researchers will collect biological samples and information about your medical history for use in neurology research. By taking part in this project, you are helping efforts to predict, prevent and treat diseases for generations to come.
You can learn more about the Biorepository for Neurological Injury by contacting a study coordinator at:
If you decide to participate in the BNI, we will ask you to fill out a consent form. You will also need to provide some health information for our database. Our staff will take a small blood sample (3 ½ tablespoons) from you, and this blood sample and your health information will be stored by Mass General for future studies.
Joining this project is optional. Your choice to join will not affect the care you get at Mass General or other hospitals. You may also choose to withdraw yourself at any time.
We take patient privacy very seriously. After you join the Biorepository for Neurological Injury, we will:
As part of the Biorepository for Neurological Injury, we may:
By joining the BNI, you will help us advance research in brain health and recovery improving the quality of life for future generations to come. Your decision of whether or not to join the BNI will not affect the care you receive at Mass General or other hospitals.
Generally, we will not return individual results from research using your samples and data to you or your doctor as there is no immediate benefit to knowing these results. Research using your sample is just a stepping stone in learning about health and disease. Most of the findings that come from studying your sample will not be relevant to your personal health. In the future, this may change.
Although you should not expect to receive individual results from your samples, patients who participate in the Biorepository for Neurological Injury may receive periodic newsletters updating participants on general results from research supported by the Biorepository.
You may read more about the Partners Healthcare Biobank by going to their website: https://biobank.partners.org/
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