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Research at Mass General
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Welcome to the website for the laboratory of Dr. Maryanne Makredes Senna at the Department of Dermatology at Massachusetts General Hospital. Our unit conducts clinical research related to hair loss including research on the causes, prevention, evaluation and management of diseases that affect hair, both in adolescents and adults.We also invite collaborators from industry, research and academia interested in hair loss diseases to get in touch by emailing HAIR@partners.org.
Meet Our Team
Maryanne M. Senna, MDPrincipal InvestigatorDr. Senna, co-director of the Hair Loss Clinic is a board-certified dermatologist who specializes in the diagnosis and treatment of hair loss. In addition to treating patients for hair loss: she is developing a specialized Alopecia Research Unit to identify new treatment methods. Diagnosed herself with alopecia in the past, Dr. Senna has personal insight and empathy for her patients.
Mariko Yasuda, MD InvestigatorDr. Yasuda, co-director of the Hair Loss Clinic is a board certified dermatologist and dermatopathologist who specializes in the diagnosis and treatment of hair loss. In addition to her clinical skills, Dr. Yasuda has additional expertise in interpreting scalp biopsy specimens in patients who have alopecia.
Lynn A. Drake, MD InvestigatorDr. Drake is a world-renown expert and lecturer on hair loss who provides additional consultations.
Martina Porter, MD Clinical Research FellowDr. Porter is currently completing a combined dermatology residency and research fellowship with a special interest in the design and conduct of clinical trials. She believes that there is a great need for more research on hair loss disorders and that this understanding will lead to better treatment options for patients in the future.
Lauren Penzi, MD Clinical Research Fellow
Dr. Penzi is pleased to join the H.A.I.R. Unit as a clinical research fellow. With a longstanding interest in dermatology and clinical research, she is committed to the study of hair loss disorder pathogenesis and the development of new treatment methods.
Athena Manatis-Lornell Clinical Research CoordinatorAthena Manatis-Lornell is the coordinator for the H.A.I.R. Unit. With a background in project management and an interest in clinical research, Athena is responsible for organizing the set up of studies and aiding in their implementation.
Retrospective chart review of patient characteristics in lichen planopilarisThe purpose of this retrospective review is to collect and analyze data on patients affected by LPP in order to gain a better understanding of the epidemiology of this disease.Role: Senna, Principal Investigator: 2016P002272: 10/31/16-10/31/18
Clinico-pathological analysis of lichen planopilarisThe purpose of this study is to better characterize the histologic and immunohistochemical staining patterns in LPP and compare them to a control group of non-scarring alopecia.Role: Senna, Principal Investigator: 2016P002867: 1/24/17-1/24/19
Design and validation of a new assessment tool for lichen planopilaris, the Boston Grade of Activity in Lichen Planopilaris (Boston GOAL)The purpose of this study is to develop an assessment tool to evaluate the severity and disease activity in lichen planopilaris. Role: Senna, Principal Investigator: 2016P002620: 2/10/17-2/10/18
Clinical and histological study of alopecia and nail dystrophy in adult patients with chronic graft versus host diseaseThe purpose of this study is to investigate the incidence of alopecia and nail dystrophy in adult patients with chronic graft versus host disease and to determine whether nail dystrophy and alopecia are predictors of more severe chronic graft versus host disease in adult cGVHD patients versus controls.Role: Senna, Principal Investigator: 2017P000262: 3/20/2017-3/20/2018
Retrospective chart review of adult patient characteristics in chronic graft versus host diseaseThe purpose of this retrospective review is to collect and analyze data on adult patients with cGVHD in order to gain a better understanding of the epidemiology of GVHD and adnexal findings affecting adult patients.Role: Senna, Principal Investigator: 2017P000389: 3/17/2017-3/17/2019
Alopecia Clinic New Patient Intake Form DatabaseThe purpose of this medical records review is to collect and analyze data on patients affected by a wide range of hair loss disorders in order to gain a better understanding of different types of alopecia and identify any commonalities between patients with the same diagnosis.Role: Senna, Principal Investigator: 2017P001024: 6/6/2017-6/6/2019
If you are interested in hearing more about potential projects, please email HAIR@partners.org
H.A.I.R. Hair Academic Research UnitMaryanne M. Senna, MDPrinciple InvestigatorPlease email us HAIR@partners.org for more information on potential projects or with any questions. We also invite you to visit the Massachusetts General Hospital Hair Loss Clinic website.
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