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Functional Genomics

Genome-wide RNAi libraries available at the Broad Institute

A critical ingredient in systems immunology is loss-of-function perturbations. Our lab is part of a consortium that has generated genome-wide mouse and human lentiviral shRNA libraries. To take advantage of this library, the Broad RNAi Platform (led by David Root) has developed the expertise and technological infrastructure to apply the RNAi library to solve biological problems. We have been working closely with the RNAi Platform to address critical problems in innate and adaptive immunity.

Principal Investigator:

  • Nir Hacohen, PhD

Please contact Dr. Nir Hacohen by e-mail (nhacohen@partners.org).

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