PET-CT

PET Core Laboratory

The PET (positron emission tomography) Core Laboratory provides a full range of technical and professional services for the design and execution of programs using PET.
Contact us by email

(617) 726-8353

Overview

The PET Core Laboratory at Massachusetts General Hospital provides a full range of technical and professional services for the design and execution of programs using Positron Emission Tomography (PET).

The PET Core Facility provides the required facilities and personnel on a per study basis to allow investigators to use PET without requiring them to acquire the needed special expertise and equipment.

 

Group Members

Personnel

Georges El Fakhri, PhD
Director, PET Core & Co-Director, NMMI
Phone: (617) 726-9640
Fax: (617) 726-6165
Email: elfakhri@pet.mgh.harvard.edu


Daniel Yokell, Pharm.D.
Manager, PET Production Chemistry
Phone: (617) 643-7541
Fax: (617) 726-5123
Email: dyokell@partners.org

Facilities & Equipment

Location of Core:

The cyclotron/radiochemistry component of the PET Core is located in the basement of the Edwards Building. The PET Research Imaging Laboratories consist of imaging cameras for human and large-animals imaging including a dedicated brain PET/CT and whole body PET, PET/CT and SPECT/CT on the MGH Main Campus, as well as a dedicated MicroPET/CT for animal imaging located at the Charlestown Navy Yard.

Major Equipment:

  • Automated Radiochemical Synthesis Systems
  • PC4096 Large Bore PET Scanner
  • Exact HR+ Large Bore PET Scanner
  • E.cam (Siemens) SPECT Systems and Planar Gamma Cameras
  • Siemens PET/CT Scanner, Symbia SPECT/CT
  • NeuroPET/CT dedicated high sensitivity brain scanner
  • VISTA small animal micro PET/CT

Fee Schedule

Service*

Internal Fee: Partners

Internal Fee: Industry

External Fee: Non-Partners AMC and Non-profit

Minimum External Fee: For-profit and Industry

For-profit and Industry

15O Gases Brain CBF Metabolism

$2,689

$4,034

$3,873

$4,276

Please contact PET Core for rates

H2150 Blood Flow

$2,637

$3,956

$3,798

$4,193

Please contact PET Core for rates

11C Compounds - QC human

$2,976

$4,464

$4,286

$4,732

Please contact PET Core for rates

11C Compounds - no QC Non-human

$1,926

$2,889

$2,773

$3,062

Please contact PET Core for rates

18F Compounds - QC human

$3,000

$4,500

$4,320

$4,770

Please contact PET Core for rates

18F Compounds - no QC human

$1,950

$2,925

$2,808

$3,101

Please contact PET Core for rates

13NH3 Cardiac Blood Flow

$2,300

$3,450

$3,312

$3,657

Please contact PET Core for rates

13N2 Lung Study - QC human

$2,459

$3,688

$3,541

$3,910

Please contact PET Core for rates

13N2 Lung Study - no QC non-human

$1,409

$2,113

$2,029

$2,240

Please contact PET Core for rates

18F Fluorodeoxyglucose (FDG) -
QC human

$2,074

$3,111

$2,987

$3,298

Please contact PET Core for rates

18F Fluorodeoxyglucose (FDG) -
no QC non-human

$1,024

$1,536

$1,475

$1,628

Please contact PET Core for rates

Micro PET imaging only
(up-to-2 hrs)

$300

$450

$432

$477

Please contact PET Core for rates

Micro PET including radiotracer
(up-to-2 hrs)

$800

$1,200

$1,152

$1,272

Please contact PET Core for rates

Micro PET additional hour

<p$100

$150

$144

$159

Please contact PET Core for rates

13N2/13NH3 Saline/Aerosol

$3,600

$5,400

$5,184

$5,724

Please contact PET Core for rates

18F Imaging only

$1,950

$2,925

$2,808

$3,101

Please contact PET Core for rates

Phantom Imaging

$1,550

$2,325

$2,232

$2,465

Please contact PET Core for rates

F18 dose human

$1,800

$2,700

$2,592

$2,862

Please contact PET Core for rates

F18 dose non-human

$950

$1,425

$1,368

$1,511

Please contact PET Core for rates

Saline Increment

$1,050

$1,575

$1,512

$1,670

Please contact PET Core for rates

Validation of radiotracer for human use

$22,000

$33,000

$31,680

$34,980

Please contact PET Core for rates

Start-up fee

$7,200

$10,800

$10,368

$11,448

Please contact PET Core for rates

Consent charge

$72

$108

$104

$115

Please contact PET Core for rates

SALSA generator validation

$2,800

 $4,200

$4,032

$4,452

Please contact PET Core for rates

Validation of radiotracer for animal use

$15,000

$22,500

$21,600

$23,850

Please contact PET Core for rates

SPECT-CT

$2,100

$3,150

$3,024

$3,339

Please contact PET Core for rates

SPECT

$2,000

$3,000

$2,880

$3,180

Please contact PET Core for rates

Cyclotron Beam Time
(per hour)

$700

$1,050

$1,008

$1,113

Please contact PET Core for rates

Pass-through

$125

$125

$180

$199

Please contact PET Core for rates

CT Angiography

$1,560

$2,340

$2,246

$2,480

Please contact PET Core for rates

IRB Renewal

$3,470

$5,205

$4,997

$5,517

Please contact PET Core for rates

Technician Training/ Site Qualification
(per hour)

$300

$450

$432

$477

Please contact PET Core for rates

 

  • *We always commit our best efforts to successfully complete scheduled studies. However, given the very nature of many PET studies that rely on manufacturing of the radiopharmaceutical and in vivo imaging, we cannot cover costs associated with uncompleted studies due to equipment failure or circumstances outside of our control.

Radiopharmceuticals

F-18

FDG*

FES (estrogen receptor)†

T807 (tau protein)‡

FPEB (mGlur5)

BFPET (myocardial perfusion)

GE180 (TSPO/PBR)†

FLT (cellular proliferation)†

 

C-11

PiB (amlyoid)‡

Altropane (Dopamine transport)

Raclopride (D2/D3 receptor imaging)

Methionine (amino acid uptake)†

Acetate (fatty acid synthase)

CO (gas)

Rolipram (PDE-4 receptor imaging)

P943 (5-HT1B)

 

N-13

Ammonia*

N2 in Saline (lung perfusion imaging)

 

O-15

C15O2 (blood flow imaging)

 

Currently in Development/Validation for Human Use at the MGH PET Core

 

F-18

THK 5351/GE-216 (tau protein)‡

FMISO (hypoxia)‡

MK-6240 (tau protein)‡

GE179 (NMDA) ‡

 

C-11

PBR-28 (TSPO/PBR)‡

(S,S)-[11C]Methylreboxetine (MeNR/MRB) – targets NET

*FDA approved
†Active IND
‡Pending/Planned IND

Getting Started

Investigators from the academic community, research laboratories and industry are welcome to use the PET Core services. Research services are accessed through contact with the professional staff leading to formalization of a research plan and subsequent review by the Scientific Management Committee. Clinical services are accessed by direct arrangement with the medical staff of the radiology department.

To access the core, please contact Chris Shambaugh at(617) 726-8353or by email at cshambaugh@partners.org.

The PET Core has mechanisms available for pilot studies.

Contact us by email

(617) 726-8353

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