CCIB DNA Core

The CCIB DNA Core at Massachusetts General Hospital is dedicated to providing high-quality research services (molecular biology, genomics and laboratory automation) and access to state-of-the-art instrumentation, methodologies and expertise.

Overview

Founded in 1995, the Massachusetts General Hospital DNA Core (now CCIB DNA Core) is a well-established major research core laboratory within the Center for Computational and Integrative Biology of Mass General in Boston.

Our state-of-the-art facility provides a wide range of high-quality, cutting-edge services (molecular biology, genomics, and laboratory automation) and access to state-of-the-art instrumentation, methodologies and expertise. The majority of our clients are investigators from Massachusetts General Hospital and the greater Partners research community. We also serve researchers from external academic research institutions as well as investigators from industry throughout the United States and across the world. Currently, we are working with more than 700 researchers within the MGH/Partners research community and with about 150 external research groups.

Mission Statement

Our mission is to accelerate fundamental scientific discoveries that will improve human health. Our professional team is committed to helping investigators solve highly diverse biological and biomedical research questions by providing a diverse portfolio of state-of-the-art services, specialized expertise, detailed advice and support. We are constantly striving to advance research productivity by reliably generating the highest quality data with rapid turn-around time and competitive pricing, and by working with our customers on an individual basis to address their specific research needs.

Visit our website

Download our printable brochure

 

Group Members

Please visit our website to meet our team.

Facilities and Equipment

CCIB DNA Core at Massachusetts General Hospital:
The Clark Building
38 Sidney Street, Suite 100
Cambridge, MA 02139

The CCIB DNA Core laboratory is located on the first floor of the Clark Building, which faces the University Park Common on Sidney Street.

Major Equipment:

  • ABI 3730xl DNA Analyzers
  • Agilent 2200 TapeStation Nucleic Acid System
  • Beckman Coulter Biomek FXP (single pod system)
  • Beckman Coulter Biomek FX (dual bridge system)
  • Beckman Coulter Biomek NXP Span-8
  • Bio-Rad CFX384 Real-Time System
  • Episonic Multifunctional Bioprocessor 1100
  • Eppendorf Mastercycler pro PCR Systems
  • Hudson RapidPick Complete Colony Picker
  • Illumina MiSeq Desktop Sequencer
  • MerMadeV DNA/RNA Oligonucleotide Synthesizer
  • Molecular Devices SpectraMax Plus 384 Absorbance Plate Reader
  • Molecular Devices SpectraMax Gemini EM Plate Reader
  • Perkin Elmer Janus Mini MDT Automated Workstation
  • Perkin Elmer TopCount NXT Microplate Scintillation and Luminescence Counter
  • Tecan Freedom EVO Automated Liquid Handler

Services

The CCIB DNA Core has a 20+ year proven track record for increasing research efficiency with trusted high-quality services at competitive rates. The facility serves as a One-Stop Shop with a diverse portfolio of solutions in molecular biology, genomics and laboratory automation. All services are provided to the greater Partners/MGH scientific community, to researchers from external academic and medical centers, and to investigators in industry.

OUR SERVICES:

Next-Generation Sequencing:

  • Complete Plasmid Sequencing (incl. automated sequence assembly)
  • CRISPR Amplicon Sequencing

Sanger DNA Sequencing

  • Plasmid Sequencing
  • PCR product Sequencing
  • Difficult Template Sequencing
  • 96-well PCR Purification

Genotyping:

  • Fragment Analysis (Microsatellite)
  • Mouse Genotyping

DNA Oligonucleotide Synthesis

  • Standard DNA Oligonucleotides
  • Modified DNA Oligonucleotides
  • Degenerate DNA Oligonucleotides
  • Oligonucleotide Purification

Laboratory Automation:

  • Custom Automation Projects
  • High-Throughput Expression Library Screening
  • 96-well Plasmid DNA Preparation

Custom Molecular Biology:

  • Customized Solutions (including custom packages of various standard services)

Fee Schedule

Visit the corresponding service fee pages on our website

Getting started

Founded in 1995, the Massachusetts General Hospital DNA Core (now CCIB DNA Core) is a well-established major research core laboratory within the Center for Computational and Integrative Biology of Mass General in Boston.

Our state-of-the-art facility provides a wide range of high-quality, cutting-edge services (molecular biology, genomics, and laboratory automation) and access to state-of-the-art instrumentation, methodologies and expertise. The majority of our clients are investigators from Massachusetts General Hospital and the greater Partners research community. We also serve researchers from external academic research institutions as well as investigators from industry throughout the United States and across the world. Currently, we are working with more than 700 researchers within the MGH/Partners research community and with about 150 external research groups.

Mission Statement

Our mission is to accelerate fundamental scientific discoveries that will improve human health. Our professional team is committed to helping investigators solve highly diverse biological and biomedical research questions by providing a diverse portfolio of state-of-the-art services, specialized expertise, detailed advice and support. We are constantly striving to advance research productivity by reliably generating the highest quality data with rapid turn-around time and competitive pricing, and by working with our customers on an individual basis to address their specific research needs.

Visit our website

Download our printable brochure

 

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