Dr. Vagefi graduated with a B.A. in Biology from Johns Hopkins University, followed by medical school at Yale. During medical school, Dr. Vagefi was a Howard Hughes Medical Institute Research Fellow at the Transplantation Biology Research Center with Dr. David H. Sachs. This work led to Dr. Vagefi being awarded the Young Investigator Award from the American Transplant Congress. Dr. Vagefi completed his general surgery residency at the Massachusetts General Hospital, followed by an abdominal transplant surgery fellowship at the University of California, San Francisco where he received the ASTS Novartis Fellowship in Transplantation Award. Dr. Vagefi's clinical expertise is in adult and pediatric liver transplantation (including split-liver and living donor liver transplantation) and complex hepatobiliary surgery. Dr. Vagefi's research lab is at the Transplantation Biology Research Center
Dr. Vagefi's research focus is to establish a clinically relevant large animal model of pig-to-baboon liver xenotransplantation, with a specific interest in donor organ pre-conditioning to facilitate tolerance induction. In addition, Dr. Vagefi performs clinical research in the field of liver transplantation.