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On any given day in the Ott Lab at the MGH a number of studies are underway. Bioreactors, each with an organ inside, are hooked to complicated networks of tubes carrying special solutions into the organ's cellular scaffolding. This is the world of Harald Ott, MD, a thoracic surgeon who leads the lab's activities.
MGH researchers have taken initial steps toward the creation of bioengineered human hearts using donor hearts stripped of components that would generate an immune response and cardiac muscle cells generated from induced pluripotent stem cells, which could come from a potential recipient.
A team of MGH investigators has made the first steps towards development of bioartificial replacement limbs suitable for transplantation.
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