James Stuart Allan, MD
Thoracic Surgery Department
55 Fruit Street, BLK 1570
Boston, MA 02114
(617) 724-1103 p
(978) 745-9024 f
jallan@partners.org

Clinical Background:

MD Degree:
Harvard Medical School

Residency:
Massachusetts General Hospital, Boston, MA
General Surgery

Fellowship:
Massachusetts General Hospital, Boston, MA
Cardiothoracic Surgery
Children's Hospital, Boston, MA
Cardiothoracic Surgery

Board Certifications:
American Board of Surgery
American Board of Thoracic Surgery

Clinical Interests:
Thoracic oncology including lung cancer, esophageal cancer, chest wall tumors, and pleural-based malignancies; benign lung and esophageal disease; lung transplantation; minimally invasive procedures; palmar hyperhidrosis; chest trauma.

Research Interests:
Transplantation immunology, including mechanisms of chronic organ rejection, the induction of immunologic tolerance, and xenotransplantation; clinical investigation; health care policy.

Recent Publications:

1. Allan JS, Sheffer EC. Case Records of the Massachusetts General Hospital: A 74-year-old man with unrelenting dysphagia. New Engl J Med, 2000; 343:199-205.

2. Allan JS, Rose GA, Choo JK, Vesga L, Mawulawde K, Slisz JK, Allison K, Madsen JC. Morphometric analysis of miniature swine hearts as potential human xenografts. Xenotransplantation, 2001; 8:90-3.

3. Allan JS, Wain JC. Diagnosis and Management of Early Graft Dysfunction Following Lung Transplantation. In: Henry M, ed., Clinical Challenges in Transplant Medicine. Princeton Healthcare Communications, Inc., 2001; 3:12-14.

4. Allan JS, Wain JC, Schwarze ML, Houser SL, Madsen JC, Sachs DH. Obliterative bronchiolitis develops in miniature swine transplanted across a minor histocompatibility barrier. Transplant Proc, 2001; 33:358-359.

5. Allan JS, Madsen JC. Recent advances in the immunology of chronic rejection. Curr Opin Nephrol Hypertens 2002; 11:315-321.

6. Allan JS, Wain JC, Schwarze ML, Houser SL, Benjamin LC, Sachs DH. Modeling chronic lung allograft rejection in miniature swine. Transplantation, 2002; 73:447-453.

7. Allan JS. Rare solitary benign tumors of the lung. Semin Thorac Cardiovasc Surg, 2003; 15:315-322.

8. Allan JS and Wright CD. Tracheoinnominate fistula: diagnosis and management. Chest Surg Clin North Am, 2003, 13:331-341.

9. Allan JS. Immunosuppression for lung transplantation. Semin Thorac Cardiovasc Surg, 2004;16:333-41.

10. Hoerbelt R, Muniappan A, Madsen JC, Allan JS. New strategies for the treatment of chronic rejection. Curr Opin Invest Drug, 2004; 5:489-498.

11. Houser SL, Benjamin LC, Wain JC, Madsen JC, Allan JS. Constitutive expression of major histocompatibility complex class II antigens in pulmonary epithelium and endothelium varies among different species. Transplantation, 2004; 77: 605-607.

12. Fynn-Thompson F, Allan JS. “Chest trauma 2: tracheobronchial and esophageal injuries.” In: Sheridan RL, ed., The Trauma Handbook of the Massachusetts General Hospital, Lippincott, Williams and Wilkins, Philadelphia, 2004; 314-327.

13. Morse CR, Allan JS. “Chest trauma 1: chest wall, pleural space, and lung parenchyma.” In: Sheridan RL, ed., The Trauma Handbook of the Massachusetts General Hospital, Lippincott, Williams and Wilkins, Philadelphia, 2004; 296-313.

14. Mutrie CJ, Donahue DM, Wain JC, Wright CD, Grillo HC, Mathisen DJ, Allan JS. Esophageal leiomyoma: a 40-year experience. Ann Thorac Surg, 2005; 79: 1122-1125.

15. Schroeder C, Allan JS, Nguyen B-N, Wu G, Zhang T, Azimzadeh A, Madsen JC, Schuurman H-J, Sachs DH, Pierson RN. Hyperacute rejection is attenuated in GalT-KO swine lungs perfused ex vivo with human blood. Transplant Proc, 2005; 37: 512-513.

16. Shoji T, Muniappan A, Guenther DA, Wain JC, Houser SL, Hoerbelt R, Benjamin LC, Hasse RS, Bravard MA, Sachs DH, Madsen JC, Allan JS. Long-term acceptance of porcine pulmonary allografts without chronic rejection. Transplant Proc, 2005; 37: 72-74.

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