Center for Transplantation Sciences

The Center for Transplantation Sciences (CTS) at Massachusetts General Hospital conducts critical research to increase the success rates of transplantation and meet the growing demand for organ and bone marrow transplantation.

Alessandrini Laboratory
Alessandrini Laboratory

The Alessandrini Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital studies regulatory T cells and plasmacytoid dendritic cells, and the roles they play in the induction of transplantation tolerance.

Benichou Laboratory
Benichou Laboratory

The Benichou Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital studies the immune mechanisms underlying the allorecognition and alloresponse by T and B cells in transplant rejection and tolerance.

Cardiothoracic Transplantation Laboratory
Cardiothoracic Transplantation Laboratory

The Cardiothoracic Transplantation Laboratory at Massachusetts General Hospital uses state-of-the-art molecular and cellular techniques to study transplantation tolerance, acute/chronic rejection, innate immunity, xenotransplantation and whole organ bioengineering for heart and lung transplantation models.

Cosimi/Kawai Laboratory
Cosimi/Kawai Laboratory

The Cosimi/Kawai Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital focuses on allograft tolerance induction in nonhuman primates and humans, with the goal of developing safe and reliable tolerance-inducing regimens for clinical transplantation.

Genetic Engineering Laboratory
Genetic Engineering Laboratory

The Genetic Engineering Laboratory in the Center for Transplantation Sciences (CTS) focuses on understanding the immune response to porcine xenografts, engineering swine for use as solid organ xenotransplantation donors and developing porcine stem cells for use in large animal models of potential stem cell therapies.

Hematopoietic Cell Transplantation Laboratory
Hematopoietic Cell Transplantation Laboratory

The Hematopoietic Cell Transplantation Laboratory in the Center for Transplantation Sciences (CTS) studies the immunology of hematopoietic cell transplantation with the goal of eliminating immunological barriers in patients with cancers and other diseases that affect the blood, bone marrow and lymph nodes.

Hoggatt Laboratory
Hoggatt Laboratory

The Hoggatt Laboratory focuses on stem cell biology and the development of novel therapies for cancer and tissue regeneration.

Kim/Markmann Laboratory
Kim/Markmann Laboratory

The Kim/Markmann Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital examines the hypothesis that a small subset of B cells plays a beneficial or regulatory role in transplant tolerance within the elderly population.

Molecular Biology Laboratory
Molecular Biology Laboratory

The Molecular Biology Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital focuses on deciphering the role of major histocompatibility class II molecules in the modulation of T cell responses to self and foreign antigens.

Organ Transplantation Tolerance and Xenotransplantation Laboratory
Organ Transplantation Tolerance and Xenotransplantation Laboratory

The Organ Transplantation Tolerance and Xenotransplantation Laboratory in the Center for Transplantation Sciences (CTS) works to develop strategies to induce tolerance across allogeneic and xenogeneic barriers to prevent rejection and relieve the current shortage of donor organs.

Pancreatic Islet Isolation Laboratory
Pancreatic Islet Isolation Laboratory

The Massachusetts General Hospital Pancreatic Islet Isolation Laboratory is a specialized service facility practicing FDA-approved Good Manufacture Procedure (cGMP) standards to manufacture human pancreatic islets.

Transplantation Biology Research Center (TBRC) Laboratories
Transplantation Biology Research Center (TBRC) Laboratories

The Transplantation Biology Research Center (TBRC) Laboratories in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital comprises two laboratories investigating tolerance induction in transplantation.

Turka Laboratory
Turka Laboratory

The Turka Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital investigates the cellular and molecular aspects of T cell tolerance, with a particular interest in mechanisms of transplant tolerance.

Vagefi Laboratory
Vagefi Laboratory

The Vagefi Laboratory in the Massachusetts General Hospital Center for Transplantation Sciences (CTS) focuses on developing tolerance-inducing strategies utilizing a preclinical model of pig-to-baboon xenotransplantation.

Vascularized Composite Allotransplantation Laboratory
Vascularized Composite Allotransplantation Laboratory

The Vascularized Composite Allotransplantation Laboratory in the Massachusetts General Hospital Center for Transplantation Sciences (CTS)investigates the immunobiology of vascularized composite allografts with a primary focus on developing tolerance induction strategies in preclinical models.

Wang Laboratory
Wang Laboratory

The Wang Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital uses a unique diphtheria toxin-resistant yeast Pichia Pastoris expression system as a platform to develop novel diphtheria toxin-based recombinant immunotoxins/fusion toxins for specific depletion of targeted cell populations in vivo.

Yeh Laboratory
Yeh Laboratory

The Yeh Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital researches ways to improve access to transplantation and reduce wait list times.


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