Lung Cancer Program
The Lung Cancer Program in Mass General's Division of Thoracic Surgery provides comprehensive, innovative treatment for lung cancer.
- Phone: 617-726-6826
Multidisciplinary Patient Care
We were among the first to create a multidisciplinary thoracic oncology clinic. Our team approach ensures that each patient benefits from an individualized, coordinated treatment plan involving thoracic oncology experts from a wide array of specialties, including:
- Thoracic surgeons, medical oncologists and radiation oncologists
- Radiologists and pathologists
- Nurse practitioners and oncology nurses
- Respiratory therapists and physical therapists
- Social workers and caseworkers, all of whom work exclusively to treat patients with thoracic cancers
Expertise in Diagnosing and Staging Thoracic Cancers
Our diagnostic and interventional radiologists, surgeons, endoscopists and pathologists are highly specialized. They have unique experience in safely and rapidly diagnosing and staging thoracic cancers. This expert analysis helps each patient’s doctors to tailor an individualized treatment plan. The plan is made on the day of the multidisciplinary visit to determine the best therapy for each patient. Appointments are usually scheduled within one week.
Imaging
We use the most advanced diagnostic imaging tools, including:
- Standard CT, MRI, PET and nuclear medicine scans
- PET/CT fusion scans
- Percutaneous needle aspiration and core biopsies
- Molecular diagnostic tests and electron microscopy
Diagnostic Procedures
We offer a number of minimally-invasive endoscopic procedures to aid in diagnosing thoracic malignancies, such as:
- Bronchoscopy to explore the bronchial passages
- Esophagoscopy to explore the esophagus
- Mediastinoscopy to explore the area between the lungs and nearby lymph nodes
- Thoracoscopy to explore the thorax
- Esophageal endoscopic ultrasound
- Endobronchial ultrasound
- Electromagnetic navigational bronchoscopy
Pathology
All thoracic specimens are reviewed by pathologists specializing in thoracic pathology. Our pathologists are recognized for their expertise in thoracic pathology, including cancers and mesotheliomas, particularly diffuse malignant mesotheliomas in connection with asbestos-related lung disease. They lecture internationally and receive requests for consultations from around the world.
Comprehensive Treatment Options
For those thoracic cancer patients whose treatment will involve surgery, chemotherapy, and radiation, or some combination of all three therapies, our integrated approach offers a unique combination of multidisciplinary care and the most advanced medical, surgical, and radiation therapies.
Our cutting-edge medical therapies include:
- Bioimagery, an advanced molecular imaging approach used to identify tumor margins following primary chemotherapy, which informs decisions about surgery
- Image-guided, minimally invasive interventions that offer an alternative to major surgery
- Minimally invasive radiofrequency ablation for patients for whom surgery is not appropriate
Consultations
Consultations can also be obtained via the Center for Thoracic Cancers at the Mass General Cancer Center. The lung cancer research program, supported by Mass General thoracic surgery, is a multifaceted effort designed to understand thoracic cancer biology, discover novel agents, and improve treatment.
Of the two major types of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer, NSCLC is more common and spreads to different parts of the body more slowly than small cell lung cancer. Squamous cell carcinoma, adenocarcinoma, and large cell carcinoma are three types of non-small cell lung cancer. Small cell lung cancer accounts for about 20% of all lung cancer.
Surgery is advised for patients with non-small cell lung cancer that has not spread outside the lung. Some patients with more advanced lung cancer are treated with a combination of surgery, radiation and chemotherapy.
Mass General thoracic surgeons perform the following resections for lung cancer:
- Minimally invasive pulmonary resections such as lobectomy, segmentectomy and wedge resections
- Sleeve lobectomy
- Pneumonectomy
- Carinal resection, carinal pneumonectomy
- Tracheal resection
- Resection of superior sulcus tumors or chest wall tumors
- Tumors involving the superior vena cava or the left atrium
Related Links
We have a rich history of clinical innovation in the treatment of thoracic disease — especially the care of lung and esophageal cancers — dating back to the 1930s. Our program provides advanced treatment for cancers involving:
- Lung
- Trachea
- Chest wall
- Mesothelioma (lining of the lung and chest wall)
Multidisciplinary Patient Care
Each patient has a medical team dedicated to his or her care. This team includes thoracic surgeons, medical oncologists, radiation oncologists, radiologists and pathologists, all of whom are among the country’s leading specialists in thoracic cancer.
These clinicians work together with the patient and his or her primary care physician to create a coordinated treatment plan for all aspects of care. We work with the patient and their referring physician throughout treatment to ensure the best possible outcome.
We also offer a wide range of free educational programs and support services designed to address the physical, psychological and spiritual needs of patients and their families.
Innovative Approaches to Cancer Treatment
Our program is a national leader in the treatment of thoracic cancers. We were the first to pioneer several of the surgical procedures and radiation therapies used to treat these cancers, and we continue to advance the field of cancer medicine with new techniques and research. We treat thousands of patients annually, and studies show that such high-volume experience results in improved patient outcomes.
Specialization also improves outcomes. Among our highly specialized services is the Francis H. Burr Proton Therapy Center. It is the Northeast’s only proton radiation facility, offering precisely-targeted radiation that eliminates tumors while reducing damage to healthy tissue. This therapy may be used for patients with certain thoracic cancers.
Striving for Better Therapies
We offer patients a multifaceted, individualized approach to care, including:
- A personalized treatment plan created and coordinated by a team of specialists in thoracic oncology
- Sophisticated and timely diagnostics
- Access to the most advanced surgical, radiation, and medical therapies
- Specialized nursing care and support services for patients and families
Novel Cancer Treatments through Clinical Trials
We are one of the nation’s foremost centers for research on thoracic cancers. Access to the latest research allows us to bring promising new treatments to patients as quickly as possible. Some of our current trials include:
- Novel therapeutics that inhibit epidermal growth factor receptor, a molecule on a tumor cell membrane that magnifies tumor growth
- "Smart drugs" that limit tumor cell growth and that can be tailored for individualized treatment for each patient
- Using gene therapy to improve the treatment of advanced lung and esophageal cancer
- Enhancing standard chemotherapy by modifying chemotherapy resistance
- Research into the genetics of lung and esophageal cancers in families to explore how genetic differences affect treatment
Maxwell V. Blum Cancer Resource Room
The Maxwell V. Blum Cancer Resource Room at the Massachusetts General Hospital Cancer Center provides cancer patients and their families with information and resources for living with cancer.
Oncology Chaplaincy
Our oncology chaplain is familiar with the unique needs of those with cancer.
Mass General Imaging introduces CT lung-cancer screening
Research shows a clear benefit for CT lung-cancer screening among individuals who meet strict criteria. Patients and referrers should understand both the benefit and the potential for false positive results.
Franco Davoli Memorial Golf Tournament
Help support ground-breaking lung cancer research at Mass General and participate in the Franco Davoli Memorial Golf Tournament on May 21st.
Cancer Breakthroughs
Research at Mass General leads to breakthroughs in cancer treatment and prevention.
Alice Shaw, MD, explains why patients with lung cancer can benefit from genetic testing
Alice Shaw, MD, thoracic oncologist at the Mass General Cancer Center, says patients with lung cancer can benefit from genetic testing, particularly if they are young non-smokers. Learn more about personalized treatment for lung cancer and new "smart drugs" that target a tumor's specific genetic mutation to slow the cancer's growth, and in some cases, reduce it significantly.
Bill Schuette's Story
Watch Bill Schuette tell the story of why he drove 18 hours each way from Ohio for lung cancer treatment at the Mass General Cancer Center.
Maxwell V. Blum Cancer Resource Room
The Maxwell V. Blum Cancer Resource Room at the Massachusetts General Hospital Cancer Center provides cancer patients and their families with information and resources for living with cancer.
Oncology Chaplaincy
Our oncology chaplain is familiar with the unique needs of those with cancer.
Division of Thoracic Surgery
55 Fruit StreetBlake 1570
Boston, MA 02114
Phone: 617-726-6826
Next Steps:
- Phone: 617-726-6826



