Massachusetts General Hospital | Transplant Center

Biography

Arthur Kim, M.D. is the Director of the Viral Hepatitis Clinic in the Division of Infectious Diseases at Massachusetts General Hospital and Assistant Professor of Medicine at Harvard Medical School. He received his medical degree at Harvard Medical School and trained in internal medicine at MGH and infectious diseases at MGH/Brigham and Women's Hospital. He expresses a longstanding interest in those living with HCV, especially in special populations such as acute infection, prisoners, post-transplantation, and HIV co-infection.  He currently is co-PI of an NIH-funded study examining the immunological outcomes of acute HCV infection and especially welcomes referrals of those suspected to have early or acute infection.

Research

My research interests are related to hepatitis C virus (HCV) infection in special populations.  I have three primary areas of focus:

1. HCV in immunosuppressed humans, including coinfection with HIV-1 and post-transplantation.  My interests are in cell-mediated immunity and HCV viral evolution in collaboration with Georg Lauer, Todd Allen

2. Immunology of acute HCV, in collaboration with Georg Lauer of the Gastrointestinal Unit

3. Acute HCV in the MA prisons.  As project leader of a U19 NIH Center Grant, I am studying acute HCV in the Massachusetts State Prisons in collaboration with Barbara McGovern at the Lemuel Shattuck Hospital and the Department of Public Health

4. Immunogenetics of HCV infection, in collaboration with Georg Lauer, Ray Chung of the Gastrointestinal Unit, and Mark Daly of the Broad Institute

Please note link to our division website and my interests:  http://www2.massgeneral.org/id/faculty/research_interests/index.asp?ID=155

Publications

Selected from 36 peer-reviewed publications: 

1. Kim AY, Lauer GM, Ouchi K, et al. The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T cell count in individuals coinfected with HIV-1. Blood. 2005;105(3):1170-1178.

2. Kim AY, Schulze zur Wiesch J, Kuntzen T, et al. Impaired HCV-specific T cell responses and recurrent HCV in HIV coinfection. PLoS Med. 2006;3(12):e492.

3. Chen TY, Ding EL, Seage GR, Kim AY. Meta-analysis: increased mortality associated with HCV in HIV-infected persons is not related to HIV disease progression.  Clin Infect Dis. 2009;49(10):1605-15.