Physician Photo

Aria F. Olumi, MD

Director, Urology Research

Co-Director, GU Oncology Clinical Program

Aria F. Olumi, MD, is a urologist at the Massachusetts General Hospital Department of Urology. He specializes in the treatment of cancer and related research.

  • Phone: 617-643-0237
Department of Urology


  • Cancer Center
  • Prostate Cancer
  • Testicular Cancer
  • Kidney Cancer
  • Bladder Cancer
  • Genitourinary Oncology
Clinical Interests
Prostate cancer
Kidney cancer
Bladder cancer
Testicular, penile and genito-urinary cancers
Laparoscopic surgery, Robotic surgery, Open surgery
Minimally invasive laser surgery for enlarged prostates
Brachytherapy (radioactive seeds) for prostate cancer
Boston: Massachusetts General Hospital
Medical Education
MD, University of Southern California Keck School of Medicine
Residency, Brigham and Women's Hospital
Fellowship, University of California, San Francisco
Board Certifications
Urology, American Board of Urology
Patient Gateway
Yes, learn more
Patient Age Group
Accepting New Patients
Accepting New Patients

ResearchDr. Olumi's laboratroy focuses on mechanisms of inducing death in cancer cells.  The laboratory has been investigating the drug, TRAIL, that induces death in cancer cells, but not normal cells, therefore, patients experience minimal side effects from the drug.  Since some cancer cells develop resistance to the drug, TRAIL, the laboratory is investigating molecular mechanisms to convert resistant cancer cells to become sensitive.  The Olumi lab has identified two novel pathways of regulating resistant cancer cells (c-Fos and FBXL10).  The research can lead to improvement of currently available cancer therapies and development of new cancer therapy agents.


View my most recent publications at PubMed

Zhang X, Zhang L, Yang H, Huang, X, Otu H, Liberman T, DeWolf WC, Khosravi-Far R, Olumi AF. c-Fos as a pro-apoptotic agent in TRAIL-induced apoptosis in prostate cancer cells. Cancer Research, 2007, 67: 9425-34.

Li W, Wu CH, Febbo PG, Olumi AF. Stromally expressed c-Jun regulates proliferation of prostate epithelial cells. American Journal of Pathology, 2007, Oct;171:1189-98.

Zhang X*, Huang X*, Olumi AF (*contributed equally). Repression of NF-kB and Activation of AP-1 Enhance Apoptosis in Prostate Cancer Cells. International Journal of Cancer. 2009;124(8):1980-9.

Olumi AF, DeWolf WC. The Hybrid of Basic Science and Clinical Training for the Urologic Oncologist: Necessity or Waste? Urologic Oncology. 2009;27:205-7.

Cystectomy: A patient education video

What to expect during admission for a cystectomy procedure. A cystectomy is a surgical procedure to removal all or part of the urinary bladder.

Nephrectomy: A patient education video

What to expect during admission for a nephrectomy procedure. A nephrectomy is a surgical procedure to remove all or part of the kidney. Surgery may involve one or both kidneys.

Prostatectomy: A patient education video

What to expect during admission for a prostatectomy procedure. A prostatectomy is a surgical procedure to remove the prostate gland.

Same day surgery procedures: A patient education video

What to expect during admission for ambulatory procedures with short recovery time, allowing discharge that day.

Prostate Health Month

September is Prostate Health Month. MGH urologists discuss the prostate, its impact on men’s health and offer advice on PSA screenings.

Mass General Urology Associates
15 Parkman St
Boston, MA 02114-3117

Phone: 617-643-0237
Fax: 617-643-4019