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Joren Christian Madsen, MD, DPHL
Director, Transplant Center
Section Chief, Cardiac Surgery
Joren Madsen, MD, DPHL, is Director of the Mass General Transplant Center, Section Chief of Cardiac Surgery, W. Gerald and Patricia R. Austen Distinguished Scholar in Cardiac Surgery and Professor of Surgery at Harvard Medical School.
- Phone: 617-643-4808
- Specialties & Programs
- Cardiac Surgery
- Heart Center
- Cardiac Surgery
- Transplant Center
- Heart Transplant
- Department of Surgery
- Clinical Interests
- Adult cardiac surgery
- Adult congenital cardiac
- Cardiac transplantation
- Medical Education
- DPHIL, Oxford University - England
- MD, University of Massachusetts Medical School
- Residency, Children's Hospital
- Residency, Massachusetts General Hospital
- Board Certifications
- Thoracic Surgery (Cardiothoracic Vascular Surgery), American Board of Thoracic Surgery (expires: 12/31/2016)
- Gender
- Male
- Patient Age Group
- Adult
- Insurance Accepted
- Aetna Health Inc.
- Best Doctors
- Blue Cross Blue Shield - Blue Care 65
- Blue Cross Blue Shield - Indemnity
- Blue Cross Blue Shield - Managed Care
- Blue Cross Blue Shield - Partners Plus
- Centene/Celticare
- Cigna (PAL #'s)
- Cigna/Healthsource NH
- EverCare
- ForMost Managed Care
- Great-West Healthcare (formally One Health Plan)
- Harvard Pilgrim Health Plan - PBO
- Harvard Pilgrim Health Plan - SSN
- Health Care Value Management (HCVM)
- Humana/Choice Care PPO
- Medicaid
- Medicare
- Neighborhood Health Plan - ACD
- Neighborhood Health Plan - PBO
- Network Health
- OSW - New Hampshire
- Private Health Care Systems (PHCS)
- Tufts Health Plan
- Tufts Medicare Advantage PPO
- Unicare
- United Healthcare (non-HMO) - PBO
Biography
Joren C. Madsen, MD, DPhil received his bachelor's degree from Brown University and his medical degree from the University of Massachusetts Medical School in 1982. After completing his first three years of general surgery training at Mass General, he was awarded the Claude E. Welch Surgical Research fellowship to study at Oxford University. His work there culminated in a doctorate degree from Balliol College in immunology. Dr. Madsen completed his surgical residency in 1990 and went on to train in cardiothoracic surgery at Mass General and Boston Children's Hospital. He joined the Division of Cardiac Surgery in 1993. Early on, Dr. Madsen focused his research efforts on the induction of immune tolerance. In 1996 he was made Director of the Cardiothoracic Immunology Laboratory and in 1999 was appointed Surgical Director of Cardiac Transplantation at Mass General.
Currently Dr. Madsen is Professor of Surgery at Harvard Medical School and the W. Gerald and Patricia R. Austen Distinguished Scholar in Cardiac Surgery at Mass General. He directs the Transplant Center, which encompasses kidney, liver, lung, heart, pancreas and small bowel transplantation in adults and children. He is also the Section Chief of Cardiac Surgery. Dr. Madsen divides his time between cardiac surgery, transplant immunology research, teaching and administration. His academic interests and over 130 publications have focused on transplantation tolerance, chronic rejection and innate immunity. He has a strong commitment to both clinical and scientific education, having mentored over 30 pre- and post-doctoral fellows in his laboratory.
Dr. Madsen serves on the editorial boards of Transplantation, the American Journal of Transplantation and the Annals of Thoracic Surgery. He is currently the president of the American Society of Transplantation, the first surgeon to be elected to that position.
Research
Dr. Madsen leads three interrelated research groups that study the molecular and cellular mechanisms of transplant rejection and immune tolerance in mice, swine and nonhuman primates, respectively. By understanding the biological of these processes Madsen hopes to find ways to prolong organ allograft survival (inducing tolerance), extend transplant recipients lives (preventing chronic rejection) and increase the organ donor pool (pig-to-human xenotransplantation). Dr. Madsen's laboratory has been the first to induce long term tolerance of cardiac allografts in large animals and to demonstrate the natural killer cells contribute to cardiac allograft vasculopathy.
Dr. Madsen is currently principal investigator on two Program Project Grants from the NIAID and NHLBI and an RO1 from the NHLBI. In addition, he directs clinical studies in heart transplantation through the Clinical Trials in Organ Transplantation (CTOT) project sponsored by the NIAID, NHLBI and NIDDK.
In 2002 he received the Fujisawa Basic Science Award from the American Society of Transplantation. In 2005 was made the W. Gerald and Patricia R. Austen Distinguished Scholar in Cardiac Surgery at Massachusetts General Hospital.
Publications
- Massachusetts General Hospital
- 55 Fruit Street
- COX 654
- Boston
- MA
- 02114-2696
- Phone: 617-643-4808
- Fax: 617-726-1821
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