Selected Recent Publications

1) Lee H-J, Selesniemi K, Niikura Y, Niikura T, Klein R, Dombkowski DM, Tilly JL. Bone marrow transplantation generates immature oocytes and rescues long-term fertility in a preclinical mouse model of chemotherapy-induced premature ovarian failure. J Clin Oncol 2007; 25: 3198-3204.

2) Tilly JL, Johnson J. Recent arguments against germ cell renewal in the adult human ovary. Is an absence of marker gene expression really acceptable evidence of an absence of oogenesis? Cell Cycle 2007; 6: 879-883.

3) Perez GI, Jurisicova A, Wise L, Lipina T, Kanisek M, Bechard A, Takai Y, Hunt P, Roder J, Grynpas M, Tilly JL. Absence of the pro-apoptotic Bax protein extends fertility and alleviates age-related health complications in female mice. Proc Natl Acad Sci USA 2007; 104: 5229-5234.

4) Johnson J, Bagley J, Skaznik-Wikiel M, Lee H-J, Adams GB, Niikura Y, Tschudy KS, Tilly JC, Cortes ML, Forkert R, Spitzer T, Iacomini J, Scadden DT, Tilly JL. Oocyte generation in adult mammalian ovaries by putative germ cells derived from bone marrow and peripheral blood. Cell 2005; 122: 303-315.

5) Perez GI, Acton BM, Jurisicova A, Perkins GA, White A, Brown J, Trbovich AM, Kim M-R, Fissore RA, Xu J, Ahmady A, D’Estaing SG, Li H, Kagawa W, Kurumizaka H, Yokoyama S, Okada H, Mak TW, Ellisman MH, Casper RF, Tilly JL. Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure. Cell Death Differ 2007; 14: 524-533.

6) Skaznik-Wikiel ME, Kaneko-Tarui T, Kashiwagi A, Pru JK. Sphingosine-1-phosphate receptor expression and signaling correlate with uterine prostaglandin-endoperoxide synthase-2 expression and angiogenesis during early pregnancy. Biol Reprod. 2006; 74(3):569-576.

7) Kaneko-Tarui T, Zhang L, Austin KJ Johnson J, Henkes L, Hansen TR, Pru JK. Maternal and embryonic control of uterine sphingolipid metabolizing enzymes during embryo implantation. Biol Reprod. 2007; 77(4):658-665.

8) Kashiwagi A, DiGirolamo CM, Kanda Y, Niikura Y, Esmon CT, Hansen T, Shioda T, Pru JK. The post-implantation embryo differentially regulates endometrial gene expression and development. Endocrinology. 2007; 148(9):4173-4184.