Carla DiGirolamo, MD, PhD

Clinical Research Fellow

Education and Training
Northeastern University, BS, Biology
MCP-Hahnemann University School of Medicine, PhD, Mol Pathobiology
Wake Forest University School of Medicine, MD

Positions and Honors
Positions and Employment:
1991-1994:      Research Assistant, US Army Research, Development & 
                         Engineering Center; Natick, MA
2001-2005:      Residency, Obstetrics/Gynecology, Women & Infants’ Hospital/Brown 
                         University School of Medicine, Providence, RI
2005- present: Clinical Research Fellow, Reproductive Medicine & Infertility, Massachusetts 
                         General Hospital/Harvard Medical School, Boston, MA
       

Professional Memberships, Honors and Awards
1993-1994: Three Exceptional Performance Awards
1993:          Northeastern University, Magna cum laude
1994:          Full Tuition Scholarship, MD/PhD program Hahnemann University School 
                   of Medicine
2002:          Award for Excellence in Resident Teaching, Women & Infants’ Hospital of RI
2003:          Dean’s Award - Excellence in Resident Teaching,  Brown University Medical School
2005:          Resident Research Award, Women & Infants’ Hospital of RI Research Day
2005:          Dean’s Award - Excellence in Resident Teaching, Brown University Medical School

Selected peer-reviewed publications
1) J.T. Prince, K.P. McGrath, C.M. DiGirolamo, D.L. Kaplan; CONSTRUCTION, CLONING AND EXPRESSION OF SYNTHETIC GENES ENCODING SPIDER DRAGLINE SILK; Biochemistry, 34(34): 10879-10885, 29 August 1995

2) S.A. Azizi, D.G. Stokes, B.J. Augelli, C.M. DiGirolamo, D.J. Prockop; ENGRAFTMENT AND MIGRATION OF HUMAN BONE MARROW STROMAL CELLS IMPLANTED IN THE BRAINS OF ALBINO RATS. SIMILARITIES TO ASTROCYTE ENGRAFTMENT; Proceedings of the National Academy of Science, USA 95(7): 3908-3913, 1998.

3) C.M. DiGirolamo, D.G. Stokes, D. Colter, D.G. Phinney and D.J. Prockop: PROPAGATION AND SENESCENCE OF HUMAN BONE MARROW STROMAL CELLS IN CULTURE. A SIMPLE COLONY FORMING ASSAY IDENTIFIES SAMPLES WITH THE GREATEST POTENTIAL FOR PROPAGATION AND DIFFERENTIATION; British Journal of Haematology 107(2): 275-281, 1999.

4) D.C. Colter, R. Class, C.M. DiGirolamo, D.J. Prockop: RAPID EXPANSION OF RECYCLING STEM CELLS IN CULTURES OF PLASTIC-ADHERENT CELLS FROM HUMAN BONE MARROW; Proceedings of the National Academy of Science, USA 97(7): 3213-3218, 2000.

5) D.J. Prockop, S.A. Azizi, D. Colter, C.M. DiGirolamo, G. Kopen, D.G. Phinney: POTENTIAL USE OF STEM CELLS FROM BONE MARROW TO REPAIR THE EXTRACELLULAR MATRIX AND THE CENTRAL NERVOUS SYSTEM; Biochemistry Society Transmission, 28(4): 341-345 2000

6) N. Tremain, J. Korkko, D. Ibberson, G.C. Kopen, C.M. DiGirolamo, D.G. Phinney: MICROSAGE ANALYSIS OF 2,353 EXPRESSED GENES IN A SINGLE CELL-DERIVED COLONY OF UNDIFFERENTIATED HUMAN MESENCHYMAL STEM CELLS REVEALS MRNA’S OF MULTIPLE CELL LINEAGES; Stem Cells, 19(5): 408-418 2001.

7) L.Liu, C.M. DiGirolamo, P.A.A. S. Narvo, M.A. Blasco, D.L. Keefe: TELOMERASE DEFICIENCY IMPAIRS DIFFERENTIATION OF MESENCHYMAL STEM CELLS; Experimental Cell Research 294: 1-8 2004.

8) R.R. Pochampally, E.M. Horwitz, C.M. DiGirolamo, D.S. Stokes, D.J. Prockop; CORRECTION OF A MINERALIZATION DEFECT BY OVEREXPRESSION OF A WILD-TYPE CDNA COL1A1 IN MARROW STROMAL CELLS (MSC’S) FROM A PATIENT WITH OSTEOGENESIS IMPERFECTA. A STRAGEGY FOR RESCUING MUTATIONS THAT PRODUCE DOMINANT NEGATIVE PROTEIN
DEFECTS; Gene Therapy 2005 12(14):1119-25.