The Vincent Center for Reproductive Biology

Anne M. Friel, PhD

Research Fellow

Education and Training:
Dublin City University, Ireland, BS, Analytical Science
National University of Ireland, Galway, PhD, Obstetrics & Gynecology

Positions and Honors:
Positions and Employment
2003-2005:     Postdoctoral Research Fellow, National University of Ireland, 
                       Dept of Obstetrics & Gynecology, Clinical Science Institute
2005-present: Postdoctoral Research Fellow, Vincent Center for Reproductive Biology,
                        Massachusetts General Hospital/Harvard Medical School 

Professional Memberships
2002-present:  Irish Network of Developmental Biologists

Selected peer-reviewed publications:

1) Dennedy MC, Friel AM, Gardeil F, Morrison JJ. Beta-3 versus beta-2 adrenergic agonists and preterm labour: in vitro uterine relaxation effects. BJOG. 2001; 108: 605-609.

2) Slattery MM, Friel AM, Healy DG, Morrison JJ. Uterine relaxant effects of cyclooxygenase-2 inhibitors in vitro. Obstet Gynecol. 2001; 98: 563-569.

3) Moran CJ, Friel AM, Smith TJ, Cairns MT, Morrison JJ. Expression and modulation of Rho kinase in human pregnant myometrium. Mol Hum Reprod. 2002; 8: 196-200.

4) Curley M, Cairns MT, Friel AM, McMeel OM, Morrison JJ, Smith TJ. Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium. Mol Hum Reprod. 2002; 8: 941-945.

5) Dennedy Mc, Friel AM, Houlihan DD, Broderick VM, Smith TJ, Morrison JJ. Cannabinoids and the human uterus during pregnancy. Am J Obstet Gynecol. 2004;190:2-9; discussion 3A.

6) O’Sullivan CJ, Allen NM, O’Loughlin AJ, Friel AM, Morrison JJ. Thrombin and PAR1-activating peptide: effects on human uterine contractility in vitro. Am J Obstet Gynecol. 2004;190:1098-1105.

7) Sexton DJ, O’Reilly MW, Friel AM, Morrison JJ. Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro. Reprod Biol Endocrinol. 2004; 2: 80-86.

8) Friel AM, Curley M, Ravikumar N, Smith TJ, Morrison JJ. Rho A/Rho kinase mRNA and protein levels in human myometrium during pregnancy and labor. J Soc Gynecol Investig. 2005; 12: 20-27.

9) O’Loughlin AJ, O’Sullivan CJ, Ravikumar N, Friel AM, Morrison JJ. Effects of thrombin, PAR-1 activating peptide and a PAR-1 antagonist on human umbilical artery resistance in vitro. Reprod Biol Endocrinol. 2005; 3:8.

10) Friel AM, O’Reilly MW, Sexton DJ, Morrison JJ. Specific PGF2a receptor (FP) antagonism and human uterine contractility in vitro. BJOG. 2005; 112: 1034-42.

11) Friel AM, Sexton DJ, O’Reilly MW, Smith TJ, Morrison JJ. Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre-eclamptic pregnancies and functional role in isoprostane induced vasoconstriction. Reproduction.2006; 132:169-76.

12) Allen NM, O’Brien M, Friel AM, Morrison JJ, Smith TJ. PAR-4 expression and modulation in human pregnant myometrium. Am J Obstet Gynecol. 2007 Feb;196(2):169.e1-6.