The Vincent Center for Reproductive Biology

Eunjeong Kwon, PhD

Research Scientist

Education and Training
Pusan National University (South Korea), BS - Biology
Pusan National University (South Korea), MS - Molecular Biology
Nagoya University (Japan), PhD - Molecular Biology

Positions and Honors
Positions and Employment
1998-2002:     Research Student, Cell Biology Laboratory, Aichi Cancer 
                       Center Research Institute (Japan)
2002-2007:     Research Fellow, Molecular Oncology Laboratory, Massachusetts
                       General Hospital/Harvard Medical School (USA) 
2007-2008:     Research Fellow, Dept of Obstetrics & Gynecology, 
                        Massachusetts General Hospital/Harvard Medical School (USA)
2008-present: Research Scientist, Vincent Center for Reproductive Biology

Honors:
1998-2002:      Japanese Government Fellowship

Selected peer-reviewed publications

1) Ryu JR, Choi TY, Kwon EJ, Lee WH, Nishida Y, Hayashi Y, Matsukage A, Yamaguchi M, Yoo MA. (1997) Transcriptional regulation of the Drosophila-raf proto-oncogene by the DNA replication-related element (DRE)/ DRE-binding factor (DREF) system, Nucleic Acids Res. 25:794-799.

2) Kwon EJ, Kim H, Kim IJ and Yoo MA, (1998) Study on roles of a number of transcription factor binding sites in the D-raf promoter region. Korean J. Biol. Sci. 2:117-122.

3) Park HS, Kim YS, Kwon EJ and Yoo MA, (1999) Analysis of the role of STAT binding site in the Drosophila-raf promoter region using transgenic flies. Korean J. Life Science 9(1):50-57.

4) Kim IJ, Kim YS, Kwon EJ, Kim H, Oh EJ and Yoo MA, (1999) Characterization of E2F site-like element in the 5-flanking region of the Drosophila raf gene. Korean J. Genetics 21(1):1-11.

5) Park SY, Choi NY, Kwon EJ and Yoo MA, (1999) Screening of transcriptional regulator of the D-raf proto-oncogene using the yeast one-hybrid system. Korean J. Life Science 9(2):52-56.

6) Kwon EJ, Park HS, Kim YS, Oh EJ, Nishida Y, Matsukage A, Yoo MA, Yamaguchi M. (2000) Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response, J.Biol.Chem.275:19824-19830

7) Kwon EJ, Oh EJ, Kim YS, Hirose F, Ohno K, Nishida Y, Matsukage A, Yamaguchi M, Yoo MA. (2001) E2F-dependent transcription of the raf proto-oncogene during Drosophila development. Nucleic Acid Res. 15:1808-14

8) Hirose F, Ohshima N, Kwon EJ, Yoshida H, Yamaguchi M (2002) Drosophila Mi-2 negatively regulates dDREF by inhibiting its DNA-binding activity. Mol Cell Biol. 14:5182-93.

9) Hwang MS, Kim YS, Choi NH, Park JH, Oh EJ, Kwon EJ, Yamaguchi M, Yoo MA (2002) The caudal homeodomain protein activates Drosophila E2F gene expression. Nucleic Acids Res. 30:5029-35.

10) Frolov MV, Stevaux O, Moon NS, Dimova D, Kwon EJ, Morris EJ, Dyson NJ (2003) G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression. Genes Dev 17:723-8.

11) Kwon E, Seto H, Hirose F, Ohshima N, Takahashi Y, Nishida Y, Yamaguchi M (2003) Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis. Gene 309:101-16.

12) Kwon E, Hayashi Y, Otsuki K, Hirose F, Nishida Y, Yoo MA, Yamaguchi M (2004) Armadillo/Pangolin regulates PCNA and DREF promoter activities. Biochim Biophys Acta 1679:256-62.

13) Yoshida H, Kwon E, Hirose F, Otsuki K, Yamada M, Yamaguchi M(2004) DREF is required for EGFR signaling during Drosophila wing vein development. Genes Cells 9:935-44.

14) Moon NS, Frolov MV, Kwon EJ, Di Stefano L, Dimova DK, Morris EJ, Taylor-Harding B, White K, Dyson NJ. (2005) Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development. Dev Cell 9:463-75.

15) Seto H, Hayashi Y, Kwon E, Taguchi O, Yamaguchi M (2006) Antagonistic regulation of the Drosophila PCNA gene promoter by DREF and Cut. Genes Cells 11:499-512.

16) Choi YJ, Kwon EJ, Park JS, Kang HS, Kim YS, Yoo MA (2007) Transcriptional regulation of the Drosophila caudal homeobox gene by bHLH-PAS proteins. Biochim Biophys Acta. 1769:41-8

17) Kwon E, Dimova DK, Taylor-Harding B, Dyson NJ. (2007) Transcriptional repressor function of the Drosophila E2F2 associated dREAM complex and its directional regulation of divergently transcribed target genes (In process)