The Vincent Center for Reproductive Biology

Maureen P. Lynch, PhD

Education and Training 
Univ. of Massachusetts (Boston), BA, Biology 
Univ. of Colorado Health Science Center (Denver), PhD, Pathology 
Univ. of California (Los Angeles), Post-Doc, Neurobiochemistry 
Univ. of Texas/MD Anderson (Smithville) Postdoc, Cancer Biology
Univ. of Massachusetts Medical Center (Worcester) Postdoc, Cell Biology

Positions and Honors
Positions and Employment:
1994-1998:      Senior Research Assistant, Pediatric Endocrinology Div., Schneider Children's 
                         Hospital, Long Island Jewish Medical Center, New Hyde Park, NY
1994-1998:      Assistant Professor of Pediatrics, Albert Einstein College of Medicine, 
                         Bronx, NY
2000- present: Senior Research Associate & Senior Laboratory Manager, Vincent 
                         Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA
2000- present: Instructor of OB/GYN and Reproductive Biology, Harvard Medical School, Boston, MA

Selected peer-reviewed publications

1) Gerschenson LG, Conti CJ, DiPaoli JR, Lieberman R, Lynch MP, Orlicky D. Estrogen and Progesterone regulation of proliferation and differentiation of rabbit uterine epithelium. Hormones and Cancer 1984; A.R. Liss, New York, pp. 119-132.

2) Lynch MP, Gerschenson LE. Cycles of proliferation and death in rabbit endometrial cells cultured on floating collagen gels. Fed Proc 1984; 43: 778.

3) Gerschenson LE, Lynch MP, Nawaz S. Evidence for cell proliferation and cell death factors regulating growth in primary endometrial cultures. J Cell Biochem 1986; 10c: L238.

4) Lynch MP, Nawaz S, Gerschenson LE. Evidence for soluble factors regulating cell death and cell proliferation in primary cultures of rabbit endometrial epithelial cells grown on collagen. Proc Natl Acad Sci, USA 1986; 83:4784-4788.

5) Nawaz S, Lynch MP, Galand P, Gerschenson LE. Hormonal regulation of cell death in rabbit uterine epithelium. Am J Pathol 1987; 127: 51-59.

6) Lynch MP, Stein GS, Lian JB. Promotion of the osteoblast phenotype expression in normal diploid osteoblasts and osteosarcoma cells by type I collagen. Mol Biol Cell 1992; 3: (Supplement 1): 74a.

7) Giminez-Conti IB, Lynch M, Roop D, Bowhmik S, Majeski P, Conti CJ. Expression of keratins in mouse vaginal epithelium. Differentiation 1994; 56: 143-151.

8) McCabe LR, Last TJ, Lynch MP, Lian JB, Stein J, Stein G. Expression of cell growth and bone phenotypic genes during the cell cycle of normal diploid osteoblasts and osteosarcoma cells. J Cell Biochem 1994; 56: 274-282.

9) Lynch MP, Stein J, Stein GS, Lian JB. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passagedrat calvarial osteoblasts: modification of genes supporting growth, adhesion, and extracellular matrix mineralization. Exp Cell Res 1995; 216: 35-45.

10) Lynch MP, Capparelli C, Stein JL, Stein GS and Lian JB. Apoptosis during bone-like tissue development in vitro. J Cell Biochem 1998; 68: 31-49.

11) Koppel RI, Saraceno MT, Geiger EF, Lynch MP, Bienkowski RS. Chelation of zinc by Bis-diamine during conotruncal septation in rat embryos is associated with apoptosis of neural crest cells. Pediatric Res 1998; 43: 23A.

12) Carambula SF, Matikainen T, Lynch MP, Flavell RA, Dias Goncalves PB, Tilly JL, Rueda BR. Caspase-3 is a pivotal mediator of apoptosis during regression of the ovarian corpus luteum. Endocrinology 2002; 143:1495-1501.

13) Pru JK, Lynch MP, Davis JS, Rueda BR. Signaling mechanisms in tumor necrosis factor alpha-induced death of microvascular endothelial cells of the corpus luteum. Reproductive Biology and Endocrinology 2003; 1:17.

14) Carambula SF, Pru JK, Lynch MP, Matikainen T, Goncalves PB, Flavell RA, Tilly JL, Rueda BR. Prostaglandin F2alpha- and FAS-activating antibody-induced regression of the corpus luteum involves caspase-8 and is defective in caspase-3 deficient mice. Reproductive Biology and Endocrinology 2003; 1:15.

15) Fanzo JC, Lynch MP, Phee H, Hyer M, Cremesti A, Grassme H, Norris JS, Coggeshall KM, Rueda BR, Pernis AB, Kolesnick R, Gulbins E. CD95 rapidly clusters in cells of diverse origins. Cancer Biology and Therapy 2003, 2:392-395.

16) Zukerberg LR, DeBernardo RL, Kirley SD, D’Apuzzo M, Lynch MP, Littell RD, Duska LR, Boring L, Rueda BR. Loss of cables, a cyclin-dependent kinase regulatory protein, is associated with the development of endometrial hyperplasia and endometrial cancer. Cancer Research 2004; 64: 202-208. (Cover Article).
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