From Mass Pike West (From Boston):
Take Exit 15 and follow instructions below for Route 95/128 Northbound.

From Mass Pike East (From Framingham / Natick):
Take Exit 14 and follow instructions below for Route 95/128 Northbound.

From Route 95/128 Northbound:
Take Exit 27B (Winter St. Waltham) passing the brick and white P.A.R.C. Building on the left of the highway. Bear right off the exit, then right over the highway. Proceed straight through the first lights, and left through the second set. The DoubleTree Hotel should now be on your right. Stay in the right lane and follow the signs that state: Second Ave/Bear Hill Rd. Turn right and then left into the parking lot of the P.A.R.C. Building.

From Route 95/128 Southbound:
Take Exit 27B (Winter St. Waltham) and bear right off the exit. Proceed straight through the first lights and left through the second set. The DoubleTree Hotel should now be on your right. Stay in the right lane and follow the signs that state: Second Ave / Bear Hill Rd. Turn right and then left into the parking lot of the P.A.R.C. Building.

From Route 93 North or South:
Take the Route 95/128 south exit and take Exit 27B – Winter Street