Physician Photo

Carlos Fernandez-del Castillo, MD

Clinical Co-director; GI Cancer Center

Director, Pancreas and Biliary Surgery Program

Dr. Fernandez-del Castillo is a gastrointestinal surgeon specialized in pancreatic and biliary diseases.

  • Phone: 617-726-5644
General and Gastrointestinal Surgery
Department of Surgery


  • Cancer Center
  • Liver Cancer
  • Pancreatic Cancer
  • Stomach Cancer
  • Colorectal Cancer
  • Gallbladder Cancer
  • Gastrointestinal Cancers
  • Digestive Healthcare Center
  • Pancreas and Biliary Center
Clinical Interests
Pancreatic disease
Pancreatobiliary surgery
Gastrointestinal surgery
Boston: Massachusetts General Hospital
Revere: MGH Revere HealthCare Center
Medical Education
MD, Universidad Autonoma De Mexico - Mexico
Residency, Instituto Nacional de la Nutricion
Fellowship, Massachusetts General Hospital
Foreign Languages
Patient Age Group
Accepting New Patients
Accepting New Patients


Dr. Fern?ndez-del Castillo is the director of the pancreas and biliary surgery program and clinical co-director of the GI cancer center at the MGH, as well as professor of surgery at Harvard Medical School. He is a widely recognized expert in pancreatic and biliary surgery, and has authored over 250 publications on pancreatic cancer, cystic tumors of the pancreas, IPMN, neuroendocrine pancreatic tumors, acute and chronic pancreatitis. He serves in the editorial board many journals, including Annals of Surgery, and Surgery.

ResearchDr. Fern?ndez-del Castillo has laboratory and clinical research focused on pathogenesis of acute pancreatitis, models of pancreatic cancer, molecular genetics of pancreatic cancer and cystic neoplasms of the pancreas, and neuroendocrine tumors.


View my most recent publications at PubMed

  1. Phase I Study of Preoperative Short-Course Chemoradiation with Proton Beam Therapy and Capecitabine for Resectable Pancreatic Ductal Adenocarcinoma of the Head.
    Hong TS, Ryan DP, Blaszkowsky LS, Mamon HJ, Kwak EL, Mino-Kenudson M, Adams J, Yeap B, Winrich B, Delaney TF, Fernandez-Del Castillo C.
    Int J Radiat Oncol Biol Phys. 2010 Apr 24.
  2. Invasive intraductal papillary mucinous carcinomas of the pancreas: predictors of survival and the role of lymph node ratio.
    Partelli S, Fernandez-Del Castillo C, Bassi C, Mantovani W, Thayer SP, Crippa S, Ferrone CR, Falconi M, Pederzoli P, Warshaw AL, Salvia R.
    Ann Surg. 2010 Mar;251(3):477-82.
  3. New metastatic lymph node ratio system reduces stage migration in patients undergoing D1 lymphadenectomy for gastric adenocarcinoma.
    Maduekwe UN, Lauwers GY, Fernandez-Del-Castillo C, Berger DL, Ferguson CM, Rattner DW, Yoon SS.
    Ann Surg Oncol. 2010 May;17(5):1267-77. Epub 2010 Jan 23.
  4. Pancreatic cysts: preoperative diagnosis and clinical management.
    Pitman MB, Lewandrowski K, Shen J, Sahani D, Brugge W, Fernandez-del Castillo C.
    Cancer Cytopathol. 2010 Feb 25;118(1):1-13. Review.
  5. Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia.
    Strobel O, Rosow DE, Rakhlin EY, Lauwers GY, Trainor AG, Alsina J, Fern?ndez-Del Castillo C, Warshaw AL, Thayer SP.
    Gastroenterology. 2010 Mar;138(3):1166-77. Epub 2009 Dec 21.

In General awards and honors

MGH Hotline 06.26.09 In General awards and honors

One patient at a time

During the fifth annual physician recognition dinner hosted Nov. 12 by the Massachusetts General Physicians Organization (MGPO), nearly 600 physicians and guests gathered to celebrate the past, present and future of MGH’s clinical contributions and to honor the memory of the late cardiologist Brian A. McGovern, MD, with the presentation of three awards in his name.

Honoring an MGH legacy

Andrew L. Warshaw, MD, who stepped down as chief of Surgery earlier this year, continues to be acknowledged for his contributions to the field, particularly pancreatic surgery.

New Radiology and Endoscopy Techniques Are Improving Treatment of Pancreatic and Biliary Disorders

Patients seeking care for pancreatic and biliary system disorders at Massachusetts General Hospital’s Digestive Healthcare Center receive the latest in diagnostic and therapeutic treatments from a collaborative team of experts, including gastroenterologists, interventional endoscopists, pathologists, medical oncologists, surgeons, radiation oncologists, and radiation therapists.

Massachusetts General Hospital
15 Parkman Street
Boston, MA 02114-3117

Phone: 617-726-5644
Fax: 617-724-3383