Publications by Irene E. Kochevar, Ph.D.

2000

Kochevar IE, Lynch MC, Zhuang S, Lambert CR. Singlet oxygen, but not oxidizing radicals, induces apoptosis in HL-60 cells. Photochem Photobiol 2000; 72:548-553.

Lin CP, Lynch MA, Kochevar IE. Reactive oxidizing species produced near the plasma membrane induce apoptosis in bovine aorta endothelial cells. Exp Cell Res 2000; 259:351-359.

Mulroy L, Kim J, Wu I, Sharper P, Melki S, Azar DT, Redmond RW, Kochevar IE. Photochemical keratodesmos for repair of lamellar corneal incisions. Invest Ophth Vis Sci 2000; 41:3335-3340.

Tartier L, McCarey YL, Biaglow JE, Kochevar IE, Held KD. Apoptosis induced by dithiothreitol in HL-60 cells shows activation of caspase-3 and is independent of mitochondria. Cell Death Differen 2000; 7:1002-1010.

Zhuang S, Demirs JT, Kochevar IE. P38 mitogen-activated protein kinase mediates Bid cleavage, mitochondria dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem 2000; 275:25939-25948.

2001

Zhuang S, Demirs JT, Kochevar IE. Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation. Oncogene 2001; 20:6764-6776.

2002

Chan BP, Kochevar IE, Redmond RW. Enhancement of porcine skin graft adherence using a light-activated process. J Surg Res 2002; 108:77-84.

2003

Nguyen B, Kochevar IE. Influence of hydration on dihydroxyacetone-induced pigmentation of stratum corneum. J Invest Dermatol 2003; 120:665-661.

Nguyen B, Kochevar IE. Factors influencing sunless tanning with dihydroxyacetone. Br J Dermatol 2003; 149:332-340.

Zhuang S, Ouedraogo GD, Kochevar IE. Down-regulation of epidermal growth factor receptor Signaling by singlet oxygen through activation of caspase-3 and protein phosphatases. Oncogene 2003; 22:4413-4424.

Zhuang S, Kochevar IE. Ultraviolet A radiation induces rapid apoptosis of human leukemia cells by Fas ligand-independent activation of the Fas death pathway. Photochem Photobiol 2003; 78:61-67.

Zhuang S, Kochevar IE. Singlet oxygen-induced activation of Akt/Protein Kinase B is independent of growth factor receptors. Photochem Photobiol 2003; 78:361-371.

2004

Kossodo S, Wong W-R, Simon G, Kochevar IE. Effects of UVR and UVR-induced cytokines on production of extracellular matrix proteins and proteases by dermal fibroblasts cultured in collagen gels. Photochem Photobiol 2004;79(1):86-93.

Proano CE, Azar DT, Mocan MC, Redmond RW, Kochevar IE. Photochemical keratodesmos as an adjunct to sutures for bonding penetrating keratoplasty corneal incisions. J Cataract Refract Surg 2004;30:2420-4.

Proano CE, Mulroy L, Jones E, Azar DT, Redmond RW, Kochevar IE. Photochemical keratodesmos for bonding corneal incisions. Invest Ophthalmol Vis Sci 2004;45(7):2177-81.

2005

Chan BP, Amann C, Yaroslavsky AN, Title C, Smink D, Zarins B, Kochevar IE, Redmond RW. Photochemical repair of Achilles tendon rupture in a rat model. J Surg Res 2005;124(2):274-9.

Kamegaya Y, Farinelli WA, Vila Echague AV, Akita H, Gallagher J, Flotte TJ, Anderson RR, Redmond RW, Kochevar IE. Evaluation of photochemical tissue bonding for closure of skin incisions and excisions. Laser Surg Med. 2005;37(4):264-70.

Wang H, Kochevar IE. Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes. Free Radic Bio Med 2005;38(7):890-7.

2006

Redmond RW, Kochevar IE. Spatially-Resolved Cellular Responses to Singlet Oxygen. Photochem Photobiol 2006; 82(5):1178-1186.

Valencia A, Kochevar IE. Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome. Free Radical Bio Med 2006 Feb;40(4):641-50.

Valencia A, Rajadurai A, Carle AB, Kochevar IE.  7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: Roles of NADPH oxidase, mitochondria, and lipid rafts.  Free Radic Bio Med. 2006;41(11):1704-18.

2007

Ibusuki S, Halbesma GJ, Randolph MA, Redmond RW, Kochevar IE, Gill TJ. Photochemically cross-linked collagen gels as three-dimensional scaffolds for tissue engineering. Tissue Eng 2007;13(8):1995-2001

Johnson TS, O’Neill AC, Motarjem P, Amman C, Zeballos JL, Bujold KE, Nguyen T, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Photochemical tissue bonding: A novel technique in peripheral nerve repair. J Surg Res 2007;143(2):224-9.

O'Neill AC, Winograd JM, Zeballos JL, Johnson TS, Randolph MA, Bujold KE, Kochevar IE, Redmond RW.  Microvascular anastomosis using a photochemical tissue bonding technique.  Laser Surg Med 2007;39(9):716-722

2008

Valencia A, Kochevar IE.  Nox1-based NADPH oxidase is the major source of UVA-induced reactive oxygen species in human keratinocytes.  J Invest Dermatol 2008;128(1):214-22

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