Low-level light therapy for healing and biostimulation

It has been known for many years that low levels of laser or non-coherent light in the red or near-infrared spectrum (LLLT) accelerate some phases of wound healing but the benefits of LLLT in wound healing and medicine in general are still controversial. Partly this may be explained by the complicated dosimetry that pertains with regard to coherence, monochromaticity, wavelength, total fluence, pulse-structure, polarization state, power density and treatment repetition.  We have developed a quantitative and reproducible model of LLLT in excisional wounds in mice that allows many of these questions to be answered. We are exploring the use of LLLT to reduce pain and inflammation in a rat arthritis model, to stimulate limb regeneration in amphibians, to promote hair regrowth, and to study stress fracture healing.

 

 

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Hamblin MR, Demidova TN. Mechanisms of Low Level Light Therapy – an Introduction. Proc SPIE; Vol 6140. in press.

Demidova TN, Hamblin MR. Wound healing stimulation in mice by low  level light. Proc SPIE; Vol 6140. in press.