ALS Trials at Mass General

A listing of ALS trials & studies currently enrolling at the Healey & AMG Center for ALS

Clinical Trial Coordination Service

The Healey & AMG Center can help you find and enroll in a clinical trial that matches your needs and condition.

Introduction to Clinical Trials

Find out how clinical trials work and why they're so important for ALS.

About Placebo-Controlled Trials

Comparison groups are a key component of clinical trials. Learn more about how they work and why they matter.

HEALEY ALS Platform Trial

We are leveraging innovative trial designs to accelerate the path to a cure for ALS.

Leaping Forward Through Collaboration

An essential element of the research efforts at the Healey & AMG Center for ALS is our commitment to a team-based approach to research.

Our investigators are dedicated to designing trials that rapidly test the benefits of promising investigational therapies for ALS and carry only the most promising forward into larger trials, thus focusing our efforts on the best therapies available. Our new studies will be tailored to the characteristics of the therapy and to trial participants based on clinical and biological factors.

... I would like to convey my dad's compliments. He told me that he felt like you all respected him and made him feel dignified and not just another number. The gentle care and concern that you showed made him feel like he is being treated by the best team. You explained such complexities in an understanding layman’s language. And we know that he was not just thrown a pill and left the rest for us to figure out.

I hope that my dad will be the first of many patients that you will have the “MERIT” to treat successfully. Your kindnesses is definitely the beginning of the recovery!

– Child of a patient at the ALS clinic

In the Lab – Potential New ALS Therapies

In this video, Ghazaleh Sadri-Vikili, PhD in the Neuroepigenetics Lab at the Healey & AMG Center for ALS discusses developing novel biomarkers to diagnose ALS earlier, identifying and targeting pathways, new discoveries and new compounds to treat ALS and the bench to bedside model at Mass General.

Building Dedicated Research Infrastructure

The Healey & AMG Center for ALS provides the infrastructure needed to radically change and accelerate the discovery of effective ALS therapies. Endowments will partially support our investigators as they focus on the following key initiatives:

  • Master trial designs that bring efficiencies and innovations of platform trials to ALS
  • Regulatory and translational science
  • Identification of actionable targets and drug discovery
  • Biomarker development to track response to treatment

By providing much-needed support, we will reduce the time gap between target identification and initiation of clinical trials. We believe strongly in identifying, supporting and mentoring the next generation of researchers continuing this tradition through our fellowship program. This will ensure the sustainability of future ALS research. The Healey & AMG Center for ALS will also support and attract new investigators and new ideas through awards and innovation seed grants.