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ALS Multidisciplinary Clinic
Neurology Access Center
The Neurological Clinical Research Institute (NCRI) was co-founded in 1994 by Dr. Merit Cudkowicz and Dr. Steven Greenberg to conduct clinical research in neurological disorders. The NCRI develops, designs, supports and manages innovative observational and interventional trials for neurological disorders. In collaboration with the Mass General Biostatistics Center, the NCRI has an impressive record of rapidly and efficiently leading small and large multi-center, international clinical trials including randomized, double-blind, double-dummy and open label designs. At the NCRI we strive to be at the cutting edge of innovative trial design to accelerate therapy development.
The mission of the NCRI is to accelerate translational research in neurological disorders through initiating and testing novel therapies. The NCRI fulfills this mission by supporting the entire therapeutic development process, including:
At the NCRI we provide core comprehensive clinical trial infrastructure services including:
Northeast ALS Consortium (NEALS)
The NCRI serves as the Clinical and Data Coordinating Center for the Northeast ALS Consortium (NEALS), a non-profit, research consortium committed to the cooperative implementation, timely completion, analysis, and reporting of clinical trials and other research studies aimed at improving patient care and understanding of the disease process of Amyotrophic Lateral Sclerosis (ALS). Together with the Barrow Neurological Institute (BNI), the two entities have supported over 40 clinical research studies in ALS.
Co-founded by Dr. Merit Cudkowicz, the NEALS Consortium was formed with the goal of bringing together leading ALS scientists and clinicians caring for ALS patients, to offer advice on the selection of the best therapies and direction of ALS research. Today there are over 125 membership sites dedicated to ALS research across North America, Israel, Australia, and Ireland.
Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT)
The NCRI is the Clinical Coordinating Center for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), a National Institute of Neurological Disorders and Stroke (NINDS) initiative. NeuroNEXT was created to conduct studies of treatments for neurological diseases through partnerships with academia, private foundations, and industry. The network is designed to expand the NINDS capability to test promising new therapies, increase the efficiency of clinical trials before embarking on larger studies, and respond quickly as new opportunities arise to test promising treatments for people with neurological disorders.
The NeuroNEXT program aims to:
For more information, visit the NeuroNEXT website: www.neuronext.org
The Mass General Neurological Clinical Research Institute has over 60 staff members dedicated to neurology clinical research.
Merit Cudkowicz, MD, MScNCRI Co-DirectorMassachusetts General Hospital617-726-9122
Steve Greenberg, MD, PhDNCRI Co-DirectorMassachusetts General Hospital
Nazem Atassi, MDNCRI Associate DirectorMassachusetts General Hospital617-643-6114
James Berry, MDNCRI Associate DirectorMassachusetts General Hospital 617-726-5097
Kristin Drake, MS, MBASenior Director Business Development, Strategic Initiatives, and NCRI Operations617-724-7076
Marianne Kearney ChaseDirector of Research Operations617-726-5893
Sarah Luppino, RNAssociate Site Director617-724-3380
Kristin SchwabDirector of Clinical Research Operations, Stroke Research Center617-726-6227
Alex ShermanDirector of Systems617-643-2935
Hong Yu, MPHDirector of Data Management617-726-5591
Beverly SmitsOperations and Project Manager617-643-7723
We are currently seeking to hire dedicated candidates to join our dynamic group team in efficiently organizing, overseeing, coordinating, and conducting small and large multi-center, international clinical trials. To view detailed job descriptions and application instructions, please visit the MGH Careers page and search for the posting ID number listed after each job title below.
Please visit the Project ALS Internship Program page for more information on our internship opportunities.
Please visit the Neurology Education page to find more information and apply for residency, fellowship and observership programs.
Innovations in ALS Clinical Trials at Mass General
Dr. Merit Cudkowicz, Chief of Neurology at Mass General Hospital discusses innovations in ALS clinical trials since she started in the field in 1994.
Biomarkers to Accelerate ALS Therapy Development
Dr. Merit Cudkowicz, Chief of Neurology, discusses biomarkers that can help to diagnose patients quicker and target individualized treatments to patients.
Neurological Clinical Research Institute (NCRI)
For General Inquires Contact
Kristin Drake Sr. Director, NCRI Email: firstname.lastname@example.org Phone: 617-724-7076
Beverly Smits Operations and Project Manager Email: email@example.com Phone: 617-643-7723
Patient Appointments & Clinical Office
ALS Multidisciplinary Clinic Phone: 617-724-3914
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