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Protocol # 08-207

Status

Recruiting

Description

This study will evaluate a method to detect tumor cells that are circulating in the blood without getting a biopsy. The investigators already know from other studies that cancer tumors shed a small number of cells into the bloodstream every day. These are called circulating tumor cells (CTCs). Some early studies indicate the amount and type of CTCs in the blood can help determine the status of the tumor itself and the way it is responding to treatment. In this study, the investigators will compare the number of CTCs in the blood at different time frames before and after surgery to remove the prostate.

Condition

  • Prostate Cancer

Study Type

Observational

Further Study Details

Primary Outcome:

  • Relationship between CTC quantity and pathologic stage
  • Persistent CTC and biochemical recurrence

Secondary Outcome:

  • Compare chromosome translocation status
  • Explore other uses of CTCs captured

Enrollment

200

Study Start Date

April 2010

Eligibility

  • Gender:     Male
  • Minimum age:     18 Years
  • Maximum age:     N/A
  • Healthy volunteers:     No

Sponsors

Massachusetts General Hospital

Source

Massachusetts General Hospital

Official title

Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

Clinicaltrials.gov Identifier

NCT01961713

     

Source: Clinicaltrials.gov. Through our founding membership in the Dana-Farber/Harvard Cancer Center, an NCI-designated Comprehensive Cancer Center, these clinical trials are conducted at the Massachusetts General Hospital Cancer Center and may be available at other partner institutions.