About Jason Efstathiou, MD,PHD,DPHIL

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Dr. Efstathiou is Professor of Radiation Oncology at Harvard Medical School (HMS) and Director of the Genitourinary (GU) Division in the Department of Radiation Oncology and Clinical Co-Director of The Claire and John Bertucci Center for GU Cancers at Massachusetts General Hospital. He holds a B.S. from Yale University, M.D. from HMS, D.Phil. from the University of Oxford, and completed his residency training in the Harvard Radiation Oncology Program.

His busy and robust clinical practice focuses on treatment of patients with prostate, bladder, testicular and other urologic cancers, as well as proton beam therapy and brachytherapy. Delivery of first-rate excellent patient care is a focus and his commitment to patient care, service and mentorship has been recognized as honoree for the MGH Cancer Center's "The One Hundred", as nominee for the Brian A. McGovern Award for Clinical Excellence, as Health Professional of the Game (for the New England Patriots and Boston Red Sox), and as a Mentor with Distinction.

He is an internationally recognized leader in the field of GU malignancies and Radiation Oncology. His research has informed clinical guidelines and made novel contributions to organ preservation for bladder cancer and technology assessment of advanced/emerging therapies for prostate cancer including proton therapy. He is the recipient of significant grant funding and serves as the Principal Investigator of multi-center, NCI-sponsored, randomized trials in prostate and bladder cancer. He also remains active in evaluating biomarkers for bladder and prostate cancer outcomes. Other projects of his include the development of web-based patient decision aids/support tools, integrating Patient Reported Outcome Measures (PROMs) into practice, evaluating the multidisciplinary approach to cancer care, and global oncology outreach efforts with Botswana.

He lectures nationally and internationally and holds leadership positions in Oncology including within the cooperative groups (NRG Oncology - Vice-Chair GU Steering Committee and Bladder Lead), professional societies (ASTRO, ASCO, ABR, ACRO), and the National Cancer Institute (NCI). He also serves on patient advocacy organizations including the Bladder Cancer Advocacy Network (BCAN) and on the Board of Directors for the Massachusetts Prostate Cancer Coalition (MPCC). 

Departments, Centers, & Programs:

Clinical Interests:



Radiation Oncology
55 Fruit Street
Boston, MA 02114-2606
Phone: 617-726-5866
Fax: 617-726-3603

Medical Education

  • MD, Harvard Medical School
  • MD, Harvard Medical School/ BWH
  • MD, Harvard University School of Public Health
  • D.Phil., University of Oxford
  • Residency, Brigham and Women's Hospital

American Board Certifications

  • Radiation Oncology, American Board of Radiology

Accepted Insurance Plans

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