September 2012

Thompson Receives MGH Award in Cancer Research
Craig B. Thompson, MD, president and chief executive officer of Memorial Sloan-Kettering Cancer Center, received the seventh annual MGH Award in Cancer Research on June 28. Presented by Daniel Haber, MD, PhD, director of the MGH Cancer Center, the award is given in memory of Nathan and Grace Shiff – parents of a former MGH research fellow – in recognition of outstanding contributions and achievements in cancer research.

Thompson is a medical oncologist with extensive research experience in cancer, immunology and translational medicine. He and his lab have pioneered the study of the BCL2 family of oncogenes and their role in regulating cell survival. His laboratory currently is focused on investigating the metabolic requirements of dividing cells and defining the molecular signaling pathways that regulate nutrient uptake. Thompson is a member of the Institute of Medicine, the National Academy of Sciences and the American Academy of Arts and Sciences.

Nabeel Bardeesy, PhD - first incumbent of the Gallagher Endowed Chair in Cancer Research
Dr. Bardeesy is an internationally recognized leader in the field of gastrointestinal cancers, with a focus on pancreatic and liver cancers. He and his colleagues have developed a series of genetically engineered mouse models harboring the most common gene mutations and have used these models to study the functional interactions of the major gene mutations associated with these cancers as well as to identify tumor biomarkers and test experimental therapeutics. Dr. Bardeesy’s primary research contributions include demonstrating the genetic interactions between oncogenic KRAS signaling and mutations in p53, p16, and Smad4, and pancreatic cancer progression and defining links between the pancreatic cancer tumor suppressor, Lkb1, and stem cell quiescence, cell metabolism and tumorigenesis in multiple tissues. Dr. Bardeesy received his BS and PhD in Biochemistry from McGill University in Montreal, Quebec. After completing his postdoctoral training at the Dana-Farber Cancer Institute/Harvard Medical School, he was recruited to the Mass General Cancer Center and appointed as an
Assistant Professor of Medicine in 2005. He was promoted to Associate Professor in May 2012.

Dr. Bardeesy is the first incumbent of the Gallagher Endowed Chair in Cancer Research. John and Kathy Gallagher made this chair possible through their generous gift, given in gratitude for the exemplary care they and their family has received from Mass General over many years. Dr. Bardeesy’s outstanding contributions in advancing our understanding of pancreatic and liver cancers will further improve patient treatment and care at MGH and worldwide.

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