Browse by Medical Category
Cutaneous Biology Research Center
A listing of the Principal Investigators at the Cutaneous Biology Research Center at Massachusetts General Hospital.
Dr. Fisher’s lab studies cell death and proliferation signals in relation to development and disease, particularly in cancer of pigment cells (melanoma) and tumors of childhood. His lab aims to understand critical modes of cell homeostasis with the goal of preventing melanoma and other human cancers and developing targeted molecular therapies.
Dr. Demehri’s lab aims to determine the role of the immune system in regulating the early stages of cancer development to harness its anti-tumor potential for cancer treatment and prevention.
Dr. Dotto’s laboratory focuses on determinants of pre-malignant to malignant tumor conversion and field cancerization, a condition of major clinical significance consisting of multifocal and recurrent tumors associated with widespread changes (cancer fields) of surrounding normal tissues.
Dr. Georgopoulous Lab's major goal is to understand how multipotent progenitors of the hematopoietic and epithelial systems utilize diverse programs in gene expression to achieve distinct fates in cellular differentiation.
Dr. Lerner’s Lab studies itch. His lab’s goal is to understand the mechanisms that underlie the sensation of itch to develop effective anti-itch therapies.
The Mandinova Laboratory uses genetic and chemical biology approaches in models of epidermal growth and differentiation to understand molecular pathways involved in stem cell decisions and tumor development in the skin.
The Manstein lab conducts basic and clinical research related to novel, energy-based procedures in dermatology.
Dr. Marneros’ Lab is interested in the molecular and cellular mechanisms that drive pathological angiogenesis. His lab’s work focuses on growth factors and inflammatory cells that regulate abnormal blood vessel formation in inflammation, wound healing, and age-related macular degeneration.
The goal of the Morgan Lab is to understand the molecular genetics of appendage formation in vertebrates.
The goal of Dr. Park’s Lab is to understand how protein kinases and their targets contribute to inflammation and immunity, and devising new methods for treating inflammatory and immune disorders.
The overall goal of the White Lab is to understand the regulation, execution, and role of apoptosis in the context of animal development, using the powerful genetic and molecular techniques available in Drosophila.
The Wu Lab focuses on studying cellular functions (self-renewal, differentiation, proliferation, and chromatin remodeling) and developmental signaling pathways using chemical and genomic tools.
The Zheng Laboratory’s research focuses on metabolic signaling in melanoma. The lab is interested in understanding how rewired metabolism in cancer cells is coordinated with other hallmarks of cancer to influence caner initiation, promotion and progression.