There are 3 main types of adrenoleukodystrophy. In the mildest form, patients have adrenal damage starting in the childhood or teenage years. Nerve involvement may occur in later life.
In the intermediate form, neurological and behavioral symptoms start in early adulthood and middle age; many have adrenal damage.
In the most severe (cerebral) form, children develop learning and behavioral problems between 4-10 years. Over time they may have difficulty reading, writing, understanding speech and written material, and adrenal gland damage.