What Causes Disorders of Sexual Development (DSD)?

There are many causes of DSD. Not all causes have yet been found. They can include:

  • Problems with the adrenal glands
  • Problems making various male hormones or the body’s inability to respond to these hormones
  • Genetic problems with the development of the sex glands (either ovary in most girls or testicle in most boys)

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Rev. 7/2019. MassGeneral Hospital for Children and Massachusetts General Hospital do not endorse any of the brands listed on this webpage. This webpage is intended to provide health information so that you can be better informed. It is not a substitute for medical advice and should not be used to treatment of any medical conditions.