Photo of Rabab Z. Jafri, MBBS

Rabab Z. Jafri, MBBS

  • Attending Physician, Pediatric Endocrinology, Massachusetts General Hospital
  • Instructor, Harvard Medical School

617-726-2909

Accepting New Patients

Overview

Rabab Jafri is an attending pediatric endocrinologist at the MassGeneral Hospital for Children. Her clinical interests include the care of children with diabetes, as well as other endocrine disorders related to the thyroid gland, adrenal gland, growth and puberty.

Departments

Pediatrics

Centers & Specialties

MassGeneral Hospital for Children

Clinical Interests
  • Diabetes mellitus type 1
  • Diabetes mellitus type 2
  • Pancreatic disease
  • Childhood obesity
  • Thyroid and adrenal disorders
  • Technological innovations in medicine
  • Technology and patient interfaces
  • Diabetes
  • Endocrinology
  • Thyroid disorders
Medical Education
  • MBBS, Aga Khan University Medical College
  • Residency, University of Illinois at Chicago Medical Center
  • Fellowship, Massachusetts General Hospital
Board Certifications
  • Pediatrics
Foreign Languages
  • Hindi
  • Urdu
Locations
  • Boston: Massachusetts General Hospital
  • Salem: North Shore Medical Center
Existing Patients
Patient Gateway
Insurances Accepted
  • Aetna Health Inc.
  • AllWays Health (NHP) - ACD
  • AllWays Health (NHP) - PBO
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • BMC HealthNet Mass Health MCO/ACO
  • Cigna (PAL #'s)
  • Commonwealth Care Alliance
  • Fallon Community HealthCare
  • Great-West Healthcare (formally One Health Plan)
  • Harvard Pilgrim Health Plan - ACD
  • Harvard Pilgrim Health Plan - PBO
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • Maine Community Health Options (MCHO)
  • MassHealth
  • Medicare
  • Medicare - ACD
  • OSW - Connecticut
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - Rhode Island
  • Private Health Care Systems (PHCS)
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Healthcare (non-HMO) - ACD
  • United Healthcare (non-HMO) - PBO
  • Well Sense Pediatrics

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.

Patient Age Group
Pediatric
Provider Gender
Female

Biography

Rabab Jafri is a pediatric endocrinologist with particular interests in pediatric diabetes and pancreatic disease. She completed a pediatric residency at the University of Illinois at Chicago, and a fellowship in pediatric endocrinology at the Massachusetts General Hospital for Children (MGHfC).  During her fellowship she became interested in diabetes related advocacy and was invited to Capitol Hill by the Endocrine Society to discuss the importance of NIH funding for research and controlling insulin pricing with state senators. Her research during fellowship involved trials with the artificial pancreas in populations with disorders of blood sugar regulation. She has presented her work at regional, national and international forums. 

Research & Publications

Research Summary

The overarching goal of my research is the incorportaion of technology within diabetes care to optimize the care of patients with disorders of glucose regulation.  Since 2016, I have been involved in trials testing the Bionic Pancreas, with the aim of automating blood glucose regulation. This is a hormonal delivery device utilizing a model predictive algorithm and delivering insulin, or, in its bi-hormonal configuration, both insulin and glucagon. This system has proven effective in patients with type 1 diabetes with ongoing studies testing its efficacy in patients with type 2 diabetes, post-bariatric hypoglycemia and congenital hyperinsulinism. I am interested in studying the differences in physiology related to the underlying mechanism behind diabetes in these conditions and what modifications to the
bionic pancreas are needed to improve glycemia in conditions other than type 1 diabetes. As part of this, I am also studying novel analogues of insulin and glucagon which are designed to provide not only optimized blood sugar control but also reduced patient burden and hence enhance quality of life. Our group is looking forward to conducting bridging and pivotal studies across multiple centers in the US in the next 1-2 years with the fully integrated dual-chamber bionic pancreas device (iLetRM).

https://sites.bu.edu/bionicpancreas/ 

Publications

View my most recent publications at PubMed

Peer reviewed publications

  1. Feki A, Berardi P, Bellingan G, Major A, Krause KH, Petignat P, Zehra R, Pervaiz S, Irminger-Finger I. Dissemination of intraperitoneal ovarian cancer: Discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model. Crit Rev Oncol Hematol. 2009 Jan 27 72(1):1-9
  2. Ansari TZ, Masood N, Parekh A, Jafri RZ, Niamatullah SN, Zaidi AA, Umer M. Four year experience of sarcoma of soft tissues and bones in a tertiary care hospital and review of literature. World J Surg Oncol. 2011 May 17;9:51.
  3. Jafri RZ, Ali A, Messonnier NE, Tevi-Benissan C, Durrheim D, Eskola J, Fermon F, Klugman KP, Ramsay M, Sow S, Zhujun S, Bhutta ZA, Abramson J.Global epidemiology of invasive meningococcal disease. Popul Health Metr. 2013 Sep 10;11(1):
  4. Ali A, Jafri RZ, Messonnier NE, Tevi-Benissan C, Durrheim D, Eskola J, Fermon F, Klugman KP, Ramsay M, Sow S, Zhujun S, Bhutta ZA, Abramson J. Global practices of meningococcal vaccine use and impact on invasive disease. Pathogens and Global Health- Pathog Glob Health. 2014 Jan;108(1):11-20.

Contact

Pediatric Endocrine Associates
55 Fruit Street
Boston, MA 02114-2696
Phone: 617-726-2909

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