Treatments

Currently Browsing:Medicine Department

Currently Browsing:Nephrology

  • Center for Renal Education

    The Center for Renal Education provides education about Chronic Kidney Disease and its management and individualized plans of care that include nutritional counseling, blood pressure management, medication review and supportive services.

  • Renal Associates Clinic

    Renal Associates provides services in general nephrology including diabetes, water and electrolyte disorders, kidney disease in pregnancy, urinary tract infections, and primary and secondary diseases of the kidney.

Currently Browsing:Pediatrics

  • Pediatric Transplant Surgery

    The Pediatric Transplant Program at MassGeneral Hospital for Children is a major referral center for organ transplants for children.

    Contact the Pediatric Transplant Program at: 617-724-1218

Currently Browsing:Surgery

Currently Browsing:Transplant Center

  • Kidney Transplant Program

    The Adult Kidney Transplant Program at Massachusetts General Hospital provides individualized, ongoing care for patients with end-stage renal disease (kidney failure).

    Request an appointment Refer a patient

    Call to make a referral 877-644-2860

  • Pancreas/Islet Transplant Program

    The Pancreas/Islet Transplant Program at the Massachusetts General Hospital Transplant Center provides innovative treatment, transplant and management options for patients with type 1 diabetes, including recent kidney transplant recipients.

    Request an appointment Refer a patient

    Call to request an appointment or refer a patient: 877-644-2860

  • Pediatric Transplant Surgery

    The Pediatric Transplant Program at MassGeneral Hospital for Children is a major referral center for organ transplants for children.

    Contact the Pediatric Transplant Program at: 617-724-1218

Currently Browsing:Transplant Surgery

About This Condition

Glomerulonephritis

What is glomerulonephritis?

When the kidneys' filters (glomeruli) become inflamed and scarred it is called glomerulonephritis. The kidneys slowly lose their ability to remove wastes and excess fluid from the blood to make urine.

What causes glomerulonephritis?

Glomerulonephritis can be caused by:

  • Toxins or medicines

  • Viral infections, such as HIV, hepatitis B, and hepatitis C

  • IgA nephropathy

  • Lupus-related kidney inflammation

  • Bacterial infections that commonly cause throat and skin infections, such as strep or staph bacteria

What are the symptoms of glomerulonephritis?

The kidneys can be badly damaged before any symptoms appear. These are the most common symptoms:

  • Fatigue

  • High blood pressure

  • Swelling of the face, hands, feet, and belly

  • Blood and protein in the urine (hematuria and proteinuria)

  • Decreased urine output

These symptoms may look like other health problems. Always talk with your healthcare provider for a diagnosis.

How is glomerulonephritis diagnosed?

Your healthcare provider will review your medical history and do a physical exam. You may need other tests, such as:

  • Urinalysis. This test checks urine for red and white blood cells, infection, or too much protein.

  • Blood tests. These tests measure the levels of waste products to find out how well the kidneys are filtering.

  • Ultrasound of the kidney. This test uses high-frequency sound waves and a computer to make images of blood vessels, tissues, and organs. It’s done to see whether the shape or size of the kidney is abnormal. Ultrasounds are used to view organs as they work, and to check blood flow through blood vessels.

  • Kidney biopsy. In this test, tissue samples are removed from the kidney and checked under a microscope.

What is the treatment for glomerulonephritis?

Treatment will depend on your symptoms, age, and general health. It will also depend on how severe the condition is.

Unfortunately, kidney disease can't be cured. Treatments focus on slowing the progression of the disease and preventing complications. Treatment may include:

  • Blood pressure medicines such as ACE (angiotensin-converting enzyme) inhibitors that protect blood flow into the kidneys

  • Corticosteroids to decrease inflammation that leads to scar tissue

  • Diuretics (water pills) to remove excess fluid in the body through more urine production

  • Diet changes including eating less protein, sodium, and potassium

  • Dialysis to remove wastes and fluid from the blood after the kidneys have stopped working

  • Kidney transplant to replace your diseased kidney with a healthy kidney from a donor

What are possible complications of glomerulonephritis?

Even with proper treatment, complications may develop. Your kidney function may decrease to the point of kidney failure. If this happens, you may need dialysis or a kidney transplant.

When should I call my healthcare provider?

If your symptoms get worse or you have new symptoms, let your healthcare provider know.

Key points about glomerulonephritis

  • Glomerulonephritis is inflammation and damage to the filtering part of the kidneys (glomeruli). It can come on quickly or over a longer period of time. Toxins, metabolic wastes, and excess fluid are not properly filtered into the urine. Instead, they build up in the body, causing swelling and fatigue.

  • The condition can progress to the point that dialysis is needed to clean the blood and remove excess fluid and toxins.

  • A kidney transplant may be needed if end-stage renal disease (ESRD) or kidney failure develops.

Next steps

Tips to help you get the most from a visit to your healthcare provider:

  • Know the reason for your visit and what you want to happen.

  • Before your visit, write down questions you want answered.

  • Bring someone with you to help you ask questions and remember what your provider tells you.

  • At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.

  • Know why a new medicine or treatment is prescribed, and how it will help you. Also know what the side effects are.

  • Ask if your condition can be treated in other ways.

  • Know why a test or procedure is recommended and what the results could mean.

  • Know what to expect if you do not take the medicine or have the test or procedure.

  • If you have a follow-up appointment, write down the date, time, and purpose for that visit.

  • Know how you can contact your provider if you have questions.