Explore This Lab

Overview

Welcome to the Hair Academic Innovative Research Unit (HAIR) led by Dr. Maryanne Makredes Senna at the Department of Dermatology at Massachusetts General Hospital. Our unit conducts clinical research related to hair loss including research on the causes, prevention, evaluation and management of diseases that affect hair, both in adolescents and adults.
We also invite collaborators from industry, research and academia interested in hair loss diseases to get in touch by emailing HAIR@partners.org.

Selected Publications

Tan S & Senna MM. Hair and Nail Manifestations of Systemic Disease. Curr Derm Rep (2017).

Xu L, Liu KX, Senna MM. A Practical Approach to the Diagnosis and Management of Hair Loss in Children & Adolescents , Front Med, 24 July 2017

Penzi LR, Manatis-Lornell AJ, Saavedra A, Fisher D, Senna MM. Hair repigmentation associated with use of Brentuximab. JAAD Case Reports 2017; 3: 563-5.

Manatis-Lornell AJ, Nikolskaia OV, Senna MM. Facial Papules in a Patient with Lichen Planopilaris. JAMA Dermatology. January 3, 2018. doi:10.1001/jamadermatol.2017.5291

Penzi LR, Manatis-Lornell AJ, Saavedra AS, Senna MM. Long-standing Pili Torti in Two Patients with Chronic Graft Versus Host Disease. JAAD Case Reports 2018 Jan; 4(1): 44–46.

Azzawi S, Penzi LR, Senna MM. Immune Privilege Collapse and Alopecia Development: Is Stress a Factor? Skin Appendage Disorders. 2017 December 20. doi: 10.1159/000485080

Rajabi F, Drake LA, Senna MM, Rezai N. Alopecia Areata: a review of disease pathogenesis. Br J Dermatol. 2018 May 23. doi: 10.1111/bjd.16808.

Naftulin JS, Penzi LR, Manatis-Lornell AJ, Yasuda MY, Porter ML, Saavedra A, Senna MM. Longstanding alopecia and nail dystrophy are associated with more severe overall chronic graft-versus-host disease in adults. Bone Marrow Transpl. 2018 Sept. doi: 10.1038/s41409-018-0309-z.

Penzi LR, Yasuda M, Manatis-Lornell A, Hagigeorges D, Senna MM. Hair Regrowth in a Patient With Long-standing Alopecia Totalis and Atopic Dermatitis Treated With Dupilumab. JAMA Dermatol. 2018 Oct 10. doi: 10.1001/jamadermatol.2018.2976 [EPub ahead of print]

Research Presented at Professional Meetings

Penzi LR, Manatis-Lornell AJ, Senna MM. Retrospective review of stress as a trigger for hair loss in patients diagnosed with alopecia areata seen in a specialty alopecia clinic. The 10th World Congress for Hair Research. Kyoto, Japan, November 1-4, 2017

Porter M, Penzi LR, Manatis-Lornell AJ, Senna MM. Retrospective review of triggers, demographics, and stress of patients diagnosed with telogen effluvium at a specialty alopecia clinic. Selected for oral presentation. The 10th World Congress for Hair Research. Kyoto, Japan, November 1-4, 2017.

Manatis-Lornell AJ, Porter M, Yasuda MR, Senna MM. Histopathological and Immunohistochemical Assessment of Patients with Lichen Planopilaris and Frontal Fibrosing Alopecia. The 10th World Congress for Hair Research. Kyoto, Japan, November 1-4, 2017.

Manatis-Lornell AJ, Porter M, Yasuda MR, Drake L, Senna MM. The use of a target area in measuring disease activity in patients with lichen planopilaris. The 10th World Congress for Hair Research. Kyoto, Japan, November 1-4, 2017.

Penzi LR, Porter M, Manatis-Lornell AJ, Senna MM. Hair disorders associated with autoimmune connective tissue diseases. Selected for oral presentation. The American Academy of Dermatology Annual Meeting, San Diego, CA. February 16, 2018.

Naftulin JS, Manatis-Lornell AJ, Penzi LR, Yasuda MR, Saavedra A, Senna MM. Categorization of long lasting hair changes in patients after hematopoietic stem cell transplant. Selected for oral presentation. The American Academy of Dermatology Annual Meeting, San Diego, CA. February 16, 2018.

Manatis-Lornell AJ, Penzi LR, Hagigeorges D, Yasuda MR, Senna MM. Patient Reported Stress Caused by Hair Loss Using A Numeric Rating Scale. The American Hair Research Society Summit Meeting, Orlando, FL. May 14-16, 2018.

Penzi LR, Manatis-Lornell AJ, Hagigeorges D, Yasuda MR, Senna MM. A Case Series of Spironolactone as An Effective Treatment for Female Pattern Hair Loss. The American Hair Research Society Summit Meeting, Orlando, FL. May 14-16, 2018

Hagigeorges D, Penzi LR, Manatis-Lornell AJ, Yasuda MR, Senna MM. The Prevalence of Misdiagnosis of Scarring Alopecia from A Facebook Scarring Alopecia Support Group Member Survey. The American Hair Research Society Summit Meeting, Orlando, FL. May 14-16, 2018.